We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Randomized trial of oral versus sublingual misoprostol 24 h after mifepristone for medical abortion.
- Authors
Dahiya, Krishna; Mann, Sonika; Nanda, Smiti
- Abstract
Objectives: To assess the efficacy, side effects, and acceptability of medical abortion using oral mifepristone (200 mg) followed 24 h later by oral or sublingual misoprostol (400 μg). Materials and methods: A total of 93 women with pregnancies up to 56 days of gestational age were assigned to two groups according to the different misoprostol regimen (group I 400 μg orally and group II 400 μg sublingually). The principle outcome measure was complete abortion defined as a complete expulsion of intrauterine contents without a need for surgical intervention 7 days after the procedure. Results: Successful abortion occurred in 87.5% of patients in group 1 and 95.5% patients in group 2 ( p = 0.166, 95% CI −0.194, 0.033). The patient acceptability and satisfaction rates were similar in both the groups. Conclusion: It is concluded that 400 μg of sublingual misoprostol is as effective as oral misoprostol 24 h after mifepristone for medical abortion of ≤56 days.
- Subjects
ABORTION; CLINICAL trials; DRUG efficacy; DRUG side effects; MISOPROSTOL; MIFEPRISTONE; ORAL drug administration; MEDICAL statistics
- Publication
Archives of Gynecology & Obstetrics, 2011, Vol 284, Issue 1, p59
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-010-1590-2