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Dose reductions in patients with Waldenström macroglobulinaemia treated with ibrutinib.
Published in:
British Journal of Haematology, 2023, v. 201, n. 5, p. 897, doi. 10.1111/bjh.18643
By:
- Sarosiek, Shayna;
- Gustine, Joshua N.;
- Flynn, Catherine A.;
- Leventoff, Carly;
- Little, Megan;
- White, Timothy;
- Meid, Kirsten;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next‐generation sequencing in Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2021, v. 194, n. 4, p. 730, doi. 10.1111/bjh.17385
By:
- Gustine, Joshua N.;
- Xu, Lian;
- Yang, Guang;
- Liu, Xia;
- Kofides, Amanda;
- Tsakmaklis, Nicholas;
- Munshi, Manit;
- Demos, Maria;
- Guerrera, Maria L.;
- Meid, Kirsten;
- Patterson, Christopher J.;
- Sarosiek, Shayna;
- Branagan, Andrew R.;
- Hunter, Zachary R.;
- Castillo, Jorge J.;
- Treon, Steven P.
Publication type:
Article
CXCR4 mutation subtypes impact response and survival outcomes in patients with Waldenström macroglobulinaemia treated with ibrutinib.
Published in:
British Journal of Haematology, 2019, v. 187, n. 3, p. 356, doi. 10.1111/bjh.16088
By:
- Castillo, Jorge J.;
- Xu, Lian;
- Gustine, Joshua N.;
- Keezer, Andrew;
- Meid, Kirsten;
- Dubeau, Toni E.;
- Liu, Xia;
- Demos, Maria G.;
- Kofides, Amanda;
- Tsakmaklis, Nicholas;
- Chen, Jiaji G.;
- Munshi, Manit;
- Guerrera, Maria L.;
- Chan, Gloria G.;
- Patterson, Christopher J.;
- Yang, Guang;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Long survival in patients with Waldenström macroglobulinaemia diagnosed at a young age.
Published in:
British Journal of Haematology, 2019, v. 185, n. 4, p. 799, doi. 10.1111/bjh.15634
By:
- Babwah, Amaara;
- Gustine, Joshua;
- Meid, Kirsten;
- Dubeau, Toni;
- Xu, Lian;
- Yang, Guang;
- Hunter, Zachary R.;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
Low levels of von Willebrand markers associate with high serum IgM levels and improve with response to therapy, in patients with Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2019, v. 184, n. 6, p. 1011, doi. 10.1111/bjh.15200
By:
- Castillo, Jorge J.;
- Gustine, Joshua N.;
- Meid, Kirsten;
- Dubeau, Toni;
- Severns, Patricia;
- Xu, Lian;
- Yang, Guang;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
TP53 mutations are associated with mutated MYD88 and CXCR4, and confer an adverse outcome in Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2019, v. 184, n. 2, p. 242, doi. 10.1111/bjh.15560
By:
- Gustine, Joshua N.;
- Tsakmaklis, Nicholas;
- Demos, Maria G.;
- Kofides, Amanda;
- Chen, Jiaji G.;
- Liu, Xia;
- Munshi, Manit;
- Guerrera, Maria L.;
- Chan, Gloria G.;
- Patterson, Christopher J.;
- Meid, Kirsten;
- Dubeau, Toni;
- Yang, Guang;
- Hunter, Zachary R.;
- Treon, Steven P.;
- Castillo, Jorge J.;
- Xu, Lian
Publication type:
Article
Response and survival for primary therapy combination regimens and maintenance rituximab in Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2018, v. 181, n. 1, p. 77, doi. 10.1111/bjh.15148
By:
- Castillo, Jorge J.;
- Gustine, Joshua N.;
- Meid, Kirsten;
- Dubeau, Toni E.;
- Severns, Patricia;
- Xu, Lian;
- Yang, Guang;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
<italic>MYD88</italic> mutations can be used to identify malignant pleural effusions in Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2018, v. 180, n. 4, p. 578, doi. 10.1111/bjh.14386
By:
- Gustine, Joshua N.;
- Meid, Kirsten;
- Hunter, Zachary R.;
- Xu, Lian;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
<italic>MYD88</italic> wild‐type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival.
Published in:
British Journal of Haematology, 2018, v. 180, n. 3, p. 374, doi. 10.1111/bjh.15049
By:
- Treon, Steven P.;
- Gustine, Joshua;
- Xu, Lian;
- Manning, Robert J.;
- Tsakmaklis, Nicholas;
- Demos, Maria;
- Meid, Kirsten;
- Guerrera, Maria L.;
- Munshi, Manit;
- Chan, Gloria;
- Chen, Jiaji;
- Kofides, Amanda;
- Patterson, Christopher J.;
- Yang, Guang;
- Liu, Xia;
- Severns, Patricia;
- Dubeau, Toni;
- Hunter, Zachary R.;
- Castillo, Jorge J.
Publication type:
Article
Serum IgM level as predictor of symptomatic hyperviscosity in patients with Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2017, v. 177, n. 5, p. 717, doi. 10.1111/bjh.14743
By:
- Gustine, Joshua N.;
- Meid, Kirsten;
- Dubeau, Toni;
- Hunter, Zachary R.;
- Xu, Lian;
- Yang, Guang;
- Ghobrial, Irene M.;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
To select or not to select? The role of B-cell selection in determining the MYD88 mutation status in Waldenström Macroglobulinaemia.
Published in:
British Journal of Haematology, 2017, v. 176, n. 5, p. 822, doi. 10.1111/bjh.13996
By:
- Gustine, Joshua;
- Meid, Kirsten;
- Xu, Lian;
- Hunter, Zachary R.;
- Castillo, Jorge J.;
- Treon, Steven P.
Publication type:
Article
Renal disease related to Waldenström macroglobulinaemia: incidence, pathology and clinical outcomes.
Published in:
British Journal of Haematology, 2016, v. 175, n. 4, p. 623, doi. 10.1111/bjh.14279
By:
- Vos, Josephine M.;
- Gustine, Joshua;
- Rennke, Helmut G.;
- Hunter, Zachary;
- Manning, Robert J.;
- Dubeau, Toni E.;
- Meid, Kirsten;
- Minnema, Monique C.;
- Kersten, Marie ‐ Jose;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
Rituximab intolerance in patients with Waldenström macroglobulinaemia.
Published in:
British Journal of Haematology, 2016, v. 174, n. 4, p. 645, doi. 10.1111/bjh.13794
By:
- Castillo, Jorge J.;
- Kanan, Sandra;
- Meid, Kirsten;
- Manning, Robert;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Overall survival and competing risks of death in patients with Waldenström macroglobulinaemia: an analysis of the Surveillance, Epidemiology and End Results database.
Published in:
British Journal of Haematology, 2015, v. 169, n. 1, p. 81, doi. 10.1111/bjh.13264
By:
- Castillo, Jorge J.;
- Olszewski, Adam J.;
- Kanan, Sandra;
- Meid, Kirsten;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Cell‐free DNA analysis for detection of MYD88<sup>L265P</sup> and CXCR4<sup>S338X</sup> mutations in Waldenström macroglobulinemia.
Published in:
American Journal of Hematology, 2021, v. 96, n. 7, p. E250, doi. 10.1002/ajh.26184
By:
- Demos, Maria G.;
- Hunter, Zachary R.;
- Xu, Lian;
- Tsakmaklis, Nicholas;
- Kofides, Amanda;
- Munshi, Manit;
- Liu, Xia;
- Guerrera, Maria Luisa;
- Leventoff, Carly R.;
- White, Timothy P.;
- Flynn, Catherine A.;
- Meid, Kirsten;
- Patterson, Christopher J.;
- Yang, Guang;
- Branagan, Andrew R.;
- Sarosiek, Shayna;
- Castillo, Jorge J.;
- Treon, Steven P.;
- Gustine, Joshua N.
Publication type:
Article
OAB-045: COVID-19 vaccine responsiveness in patients with Multiple Myeloma and Waldenström Macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S29, doi. 10.1016/S2152-2650(21)02119-4
By:
- Branagan, Andrew;
- Lei, Matthew;
- Yee, Andrew J.;
- O'Donnell, Elizabeth;
- Castillo, Jorge J.;
- Raje, Noopur;
- Treon, Steven P.;
- Flynn, Catherine;
- Burke, Jill;
- Harrington, Cynthia;
- Agyemang, Emerentia;
- Mo, Clifton;
- Nadeem, Omar;
- Richardson, Paul G.;
- Maebius, Allison;
- Onyewadume, Chukwuamaka;
- Panaroni, Cristina;
- Meid, Kirsten;
- Bernstein, Zachary;
- Lyons, Rebecca
Publication type:
Article
CXCR4 S338X clonality is an important determinant of ibrutinib outcomes in patients with Waldenström macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e316, doi. 10.1016/j.clml.2019.09.520
By:
- Gustine, Joshua;
- Xu, Lian;
- Tsakmaklis, Nickolas;
- Demos, Maria;
- Kofides, Amanda;
- Chen, Jiaji;
- Liu, Xia;
- Munshi, Manit;
- Guerrera, Maria Luisa;
- Chan, Gloria;
- Patterson, Christopher;
- Keezer, Andrew;
- Meid, Kirsten;
- Dubeau, Toni;
- Yang, Guang;
- Hunter, Zachary;
- Treon, Steven;
- Castillo, Jorge
Publication type:
Article
MYD88 and CXCR4 Mutation Rates by Allele-Specific PCR Compared with Diagnostic Next Generation Sequencing Panels in Patients with Waldenstrom's Macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e317, doi. 10.1016/j.clml.2019.09.521
By:
- Kofides, Amanda;
- Xu, Lian;
- Demos, Maria;
- Tsakmaklis, Nickolas;
- Liu, Xia;
- Yang, Guang;
- Munshi, Manit;
- Chen, Jiaji;
- Guerrera, Maria Luisa;
- Chan, Gloria;
- Jimenez, Cristina;
- Meid, Kirsten;
- Keezer, Andrew;
- Patterson, Christopher;
- Hunter, Zachary;
- Castillo, Jorge;
- Treon, Steven
Publication type:
Article
The BCR component SYK is activated by mutated MYD88 and the combined inhibition of SYK and BTK produces synthetic lethality in MYD88 driven B-cell lymphomas.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e338, doi. 10.1016/j.clml.2019.09.556
By:
- Munshi, Manit;
- Liu, Xia;
- Chen, Jiaji;
- Xu, Lian;
- Tsakmaklis, Nickolas;
- Demos, Maria;
- Kofides, Amanda;
- Guerrera, Maria Luisa;
- Chan, Gloria;
- Jimenez, Cristina;
- Hunter, Zachary;
- Patterson, Christopher;
- Meid, Kirsten;
- Keezer, Andrew;
- Castillo, Jorge;
- Treon, Steven;
- Yang, Guang
Publication type:
Article
Mutated MYD88 regulates transcription of the pro-survival kinase HCK in MYD88 driven B-cell lymphomas.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e338, doi. 10.1016/j.clml.2019.09.557
By:
- Chen, Jiaji;
- Liu, Xia;
- Munshi, Manit;
- Xu, Lian;
- Tsakmaklis, Nickolas;
- Demos, Maria;
- Kofides, Amanda;
- Guerrera, Maria Luisa;
- Chan, Gloria;
- Jimenez, Cristina;
- Hunter, Zachary;
- Patterson, Christopher;
- Meid, Kirsten;
- Keezer, Andrew;
- Castillo, Jorge;
- Treon, Steven;
- Yang, Guang
Publication type:
Article
Distribution of circulating tumor cells in Waldenström's Macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e337, doi. 10.1016/j.clml.2019.09.554
By:
- Xu, Lian;
- Kofides, Amanda;
- Demos, Maria;
- Tsakmaklis, Nickolas;
- Liu, Xia;
- Munshi, Manit;
- Chen, Jiaji;
- Guerrera, Maria Luisa;
- Jimenez, Cristina;
- Chan, Gloria;
- Patterson, Christopher;
- Meid, Kirsten;
- Keezer, Andrew;
- Yang, Guang;
- Castillo, Jorge;
- Hunter, Zachary;
- Treon, Steven
Publication type:
Article
Cell-Free DNA as Alternative to Bone Marrow CD19+ Selection for Diagnostic MYD88 L265P in Waldenstrom's Macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e311, doi. 10.1016/j.clml.2019.09.511
By:
- Demos, Maria;
- Xu, Lian;
- Tsakmaklis, Nickolas;
- Kofides, Amanda;
- Chen, Jiaji;
- Munshi, Manit;
- Liu, Xia;
- Jimenez, Cristina;
- Chan, Gloria;
- Guerrera, Maria Luisa;
- Meid, Kirsten;
- Keezer, Andrew;
- Yang, Guang;
- Hunter, Zachary;
- Castillo, Jorge;
- Treon, Steven
Publication type:
Article
Multicenter prospective phase II study of venetoclax in patients with previously treated Waldenstrom macroglobulinemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e39, doi. 10.1016/j.clml.2019.09.060
By:
- Castillo, Jorge;
- Allan, John;
- Siddiqi, Tanya;
- Advani, Ranjana;
- Keezer, Andrew;
- Gustine, Joshua;
- Meid, Kirsten;
- Dubeau, Toni;
- Lam, Jessica;
- Xu, Lian;
- Yang, Guang;
- Hunter, Zachary;
- Furman, Richard;
- Davids, Matthew;
- Treon, Steven
Publication type:
Article
Impact of Chromosome 6q Deletions in Multiple Myeloma and Waldenström's Macroglobulinemia by Next Generation RNA Sequencing.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e39, doi. 10.1016/j.clml.2019.09.059
By:
- Guerrera, Maria Luisa;
- Jimenez, Cristina;
- Chan, Gloria;
- Xu, Lian;
- Kofides, Amanda;
- Demos, Maria;
- Tsakmaklis, Nickolas;
- Liu, Xia;
- Munshi, Manit;
- Chen, Jiaji;
- Patterson, Christopher;
- Tai, Yu-Tzu;
- Samur, Mehmet;
- Fulciniti, Mariateresa;
- Meid, Kirsten;
- Keezer, Andrew;
- Castillo, Jorge;
- Yang, Guang;
- Munshi, Nikhil;
- Treon, Steven
Publication type:
Article
SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas.
Published in:
Blood Cancer Journal, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41408-020-0277-6
By:
- Munshi, Manit;
- Liu, Xia;
- Chen, Jiaji G.;
- Xu, Lian;
- Tsakmaklis, Nickolas;
- Demos, Maria G.;
- Kofides, Amanda;
- Guerrera, Maria Luisa;
- Jimenez, Cristina;
- Chan, Gloria G.;
- Hunter, Zachary R.;
- Palomba, M. Lia;
- Argyropoulos, Kimon V.;
- Meid, Kirsten;
- Keezer, Andrew;
- Gustine, Joshua;
- Dubeau, Toni;
- Castillo, Jorge J.;
- Patterson, Christopher J.;
- Wang, Jinhua
Publication type:
Article
CXCR4 mutational status does not impact outcomes in patients with Waldenström macroglobulinemia treated with proteasome inhibitors.
Published in:
American Journal of Hematology, 2020, v. 95, n. 4, p. E95, doi. 10.1002/ajh.25730
By:
- Castillo, Jorge J.;
- Gustine, Joshua N.;
- Meid, Kirsten;
- Flynn, Catherine A.;
- Demos, Maria G.;
- Guerrera, Maria L.;
- Jimenez, Cristina;
- Kofides, Amanda;
- Xia Liu;
- Munshi, Manit;
- Tsakmaklis, Nicholas;
- Patterson, Christopher J.;
- Lian Xu;
- Guang Yang;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Deepening of response after completing rituximab-containing therapy in patients with Waldenstrom macroglobulinemia.
Published in:
American Journal of Hematology, 2020, v. 95, n. 4, p. 372, doi. 10.1002/ajh.25712
By:
- Castillo, Jorge J.;
- Gustine, Joshua N.;
- Keezer, Andrew;
- Meid, Kirsten;
- Flynn, Catherine A.;
- Dubeau, Toni E.;
- Chan, Gloria;
- Jiaji Chen;
- Demos, Maria G.;
- Guerrera, Maria L.;
- Jimenez, Cristina;
- Kofides, Amanda;
- Xia Liu;
- Munshi, Manit;
- Tsakmaklis, Nicholas;
- Patterson, Christopher J.;
- Lian Xu;
- Guang Yang;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Ibrutinib discontinuation in Waldenström macroglobulinemia: Etiologies, outcomes, and IgM rebound.
Published in:
American Journal of Hematology, 2018, v. 93, n. 4, p. 511, doi. 10.1002/ajh.25023
By:
- Gustine, Joshua N.;
- Meid, Kirsten;
- Dubeau, Toni;
- Severns, Patricia;
- Hunter, Zachary R.;
- Guang, Yang;
- Xu, Lian;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
Comparing apples to oranges: A commentary on the Mayo study of MYD88 significance in Waldenstrom's macroglobulinemia.
Published in:
American Journal of Hematology, 2018, v. 93, n. 3, p. E69, doi. 10.1002/ajh.24997
By:
- Castillo, Jorge J.;
- Gustine, Joshua N.;
- Meid, Kirsten;
- Xu, Lian;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Histological transformation to diffuse large B-cell lymphoma in patients with Waldenström macroglobulinemia.
Published in:
American Journal of Hematology, 2016, v. 91, n. 10, p. 1032, doi. 10.1002/ajh.24477
By:
- Castillo, Jorge J.;
- Gustine, Joshua;
- Meid, Kirsten;
- Dubeau, Toni;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Atrial fibrillation associated with ibrutinib in Waldenström macroglobulinemia.
Published in:
American Journal of Hematology, 2016, v. 91, n. 6, p. E312, doi. 10.1002/ajh.24366
By:
- Gustine, Joshua N.;
- Meid, Kirsten;
- Dubeau, Toni E.;
- Treon, Steven P.;
- Castillo, Jorge J.
Publication type:
Article
Survival outcomes of secondary cancers in patients with waldenström macroglobulinemia: An analysis of the SEER database.
Published in:
American Journal of Hematology, 2015, v. 90, n. 8, p. 696, doi. 10.1002/ajh.24052
By:
- Castillo, Jorge J.;
- Olszewski, Adam J.;
- Kanan, Sandra;
- Meid, Kirsten;
- Hunter, Zachary R.;
- Treon, Steven P.
Publication type:
Article
Incidence of secondary malignancies among patients with Waldenström macroglobulinemia: An analysis of the SEER database.
Published in:
2015
By:
- Castillo, Jorge J.;
- Olszewski, Adam J.;
- Hunter, Zachary R.;
- Kanan, Sandra;
- Meid, Kirsten;
- Treon, Steven P.
Publication type:
journal article
A pilot study on dasatinib in patients with Waldenström macroglobulinemia progressing on ibrutinib.
Published in:
EJHaem, 2022, v. 3, n. 3, p. 927, doi. 10.1002/jha2.493
By:
- Castillo, Jorge J.;
- Sarosiek, Shayna;
- Flynn, Catherine A.;
- Leventoff, Carly;
- Little, Megan;
- White, Timothy;
- Meid, Kirsten;
- Treon, Steven P.
Publication type:
Article

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