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- Title
Sodium Extrusion in Muscle.
- Authors
SHAW, F. H.; SIMON, SHIRLEY E.
- Abstract
THE extrusion of sodium from the living cell against a concentration gradient has been demonstrated by Steinbach1, Desmedt2 and Maizels3. The mechanism of such an extrusion is often referred to as a 'sodium pump'. We have repeated the above experiment with nerve and muscle; but we find it difficult to obtain consistent results, because toad (Bufo marinus) tissue does not always lose potassium and gain sodium in the cold. This pump is not entirely activated by temperature change, as the above authors neglect to stress that extrusion of sodium does not take place unless the external potassium is increased above physiological level.
- Publication
Nature, 1955, Vol 176, Issue 4491, p1031
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/1761031b0