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- Title
Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney.
- Authors
Yang, N; Wu, LL; Nikolic-Paterson, DJ; Ng, YY; Yang, WC; Mu, W; Gilbert, RE; Cooper, ME; Atkins, RC; Lan, HU
- Abstract
Background. We have recently shown that blockade of angiotensin II activity inhibits local macrophage and myofibroblast proliferation in progressive non-immune renal injury in the rat remnant kidney. However, it is not known whether this local proliferation contributes to macrophages and myofibroblast accumulation and the development of renal injury. Therefore, we examined this issue in a detailed time-course study of the rat remnant kidney.
- Publication
Nephrology Dialysis Transplantation, 1998, Vol 13, Issue 8, p1967
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/13.8.1967