We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Feasibility of diffusion-weighted imaging with DWIBS in staging Hodgkin lymphoma in pediatric patients: comparison with PET/CT.
- Authors
Baranska, Dobromila; Matera, Katarzyna; Podgorski, Michal; Gorska-Chrzastek, Magdalena; Krajewska, Karolina; Trelinska, Joanna; Grzelak, Piotr
- Abstract
Objective: The aim of the study was to evaluate feasibility of diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) method in diagnosing Hodgkin lymphoma in pediatric patients and to compare it with 18F-FDG PET/CT as a gold standard. Materials and methods: Eleven patients (median age 14) with newly diagnosed Hodgkin lymphoma were examined with 18F-FDG PET/CT and MRI including whole-body DWIBS sequence (b = 0, 800 s/mm2), before the oncologic treatment. About 26 locations of lymphatic tissues were evaluated visually and quantitatively using ADCmean (DWIBS) and SUVmax (18F-FDG PET/CT), respectively. Results: All affected lymph node regions (n = 134) diagnosed in 18F-FDG PET/CT were found with DWIBS, presenting decreased diffusion. Significant correlation was found between ADC and SUV values (R2 = − 0.37; p = 0.0001). Nevertheless, additional 33 regions were recognized only by DWIBS. They were significantly smaller than regions diagnosed by both methods. Discussion: Agreement between DWIBS and 18F-FDG PET/CT for detection and staging of malignant lymphoma is high. DWIBS can be used for the evaluation of pediatric Hodgkin lymphoma.
- Subjects
POSITRON emission tomography computed tomography; DIFFUSION magnetic resonance imaging; HODGKIN'S disease; LYMPHOID tissue
- Publication
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine, 2019, Vol 32, Issue 3, p381
- ISSN
0968-5243
- Publication type
Article
- DOI
10.1007/s10334-018-0726-4