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- Title
Factors Associated with Tuberculosis Outcome in a Hyperendemic City in the North of Brazil.
- Authors
Costa, Gabriel Fazzi; Garcez, Juliana Conceição Dias; Marcos, Weber; Ferreira, Ana Lúcia da Silva; Andrade, Jorge Alberto Azevedo; Rodrigues, Yan Corrêa; Lima, Luana Nepomuceno Gondim Costa; Conceição, Emilyn Costa; Lima, Karla Valéria Batista
- Abstract
Ananindeua city, State of Pará, North of Brazil, is a hyperendemic area for tuberculosis (TB), with a cure rate below the recommendation by the Brazilian Ministry of Health. We aimed to describe: (I) the TB incidence coefficient of Ananindeua municipality comparatively against Brazilian data; (II) TB treatment outcomes; (III) to compare the socioeconomic and epidemiological characteristics of abandonment versus cure outcome; and (IV) to evaluate the risk factors associated with TB treatment abandonment in Ananindeua city, from 2017 to 2021. This is a retrospective, descriptive, and cross-sectional epidemiological study which used secondary TB entries. Data were analyzed by linear regression, descriptive statistics, and associations were made using the Chi-square test and G-test, followed by univariate and multivariate logistic regression analyses. Cure rates ranged from 28.7% to 70.1%, abandonment between 7.3% and 11.8%, deaths from the disease ranged from 0% to 1.6%, and drug-resistant tuberculosis (TB-DR) rates had frequencies from 0% to 0.9%. Patient transfer rates to other municipalities were between 4.9% and 12.5%. The multivariate analysis showed that alcohol is almost 2 times more likely to lead an individual to abandon treatment and use of illicit drugs was almost 3 times more likely. Individuals between 20 and 59 years of age were also more likely to abandon treatment almost twice as often. Finally, data obtained in the present report is of great relevance to strengthen epidemiological surveillance and minimize possible discrepancies between the information systems and the reality of public health in high endemicity areas.
- Subjects
BRAZIL; TUBERCULOSIS epidemiology; TUBERCULOSIS mortality; TUBERCULOSIS treatment; PATIENT refusal of treatment; STATISTICS; LOCAL government; CROSS-sectional method; RESEARCH methodology; MULTIVARIATE analysis; HEALTH outcome assessment; RETROSPECTIVE studies; REGRESSION analysis; SOCIOECONOMIC factors; DESCRIPTIVE statistics; CHI-squared test; RESEARCH funding; LOGISTIC regression analysis; ALCOHOLS (Chemical class); DRUGS of abuse; EPIDEMIOLOGICAL research
- Publication
Healthcare (2227-9032), 2023, Vol 11, Issue 4, p508
- ISSN
2227-9032
- Publication type
Article
- DOI
10.3390/healthcare11040508