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- Title
龙血竭胶囊合九华膏对环状混合痔术后患者创面愈合、血清炎性因子和 免疫功能的影响.
- Authors
孙嘉伟; 刘 欣; 马媛媛; 卢 秀; 朱孟琳
- Abstract
To investigate the effect of Longxuejie capsule combined with Jiuhua ointment on wound healing, serum inflammatory factors and immune function after operation of patients with circular mixed hemorrhoids (RMH). 93 patients with RMH admitted to our hospital from July 2016 to December 2019 were selected, they were divided into control group (n=46, Ma Yinglong musk Hemorrhoid Ointment treatment) and study group (n=47, Longxuejie capsule combined with Jiuhua ointment treatment). The curative effect, wound healing, adverse reactions serum inflammatory factors and immune function of the two groups were compared. 10 d after treatment, the total clinical effective rate of the study group was 89.36% (42/47), which was higher than 71.74% (33/46) of the control group (P<0.05). The wound exudation, edema, pain, wound granulation tissue score and wound area of the two groups at 10 d after treatment decreased, and those of study group were lower than those of control group(P<0.05). Tumor necrosis factor - 琢 (TNF-琢), interleukin-6(IL-6) and interleukin-2(IL-2) were all decreased of the two groups at 10d after treatment, and those of study group were lower than those of control group (P<0.05). Immunoglobulin G(IgG), immunoglobulin A(IGA) and immunoglobulin M(IgM) increased in both groups at 10d after treatment, and those of study group were higher than those of control group (P<0.05). The incidence of complications in the study group was lower than that in the control group (P<0.05). Patients with RMH are used Longxuejie capsule combined with Jiuhua ointment treatment is effective, which can effectively promote wound healing, reduce inflammatory reaction, improve immune function, at the same time, it can reduce the incidence of complications.
- Subjects
TUMOR necrosis factors; IMMUNOGLOBULIN M; IMMUNOGLOBULIN G; GRANULATION tissue; WOUND healing; HEMORRHOIDS
- Publication
Progress in Modern Biomedicine, 2020, Vol 20, Issue 19, p3695
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2020.19.019