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- Title
Transient Neonatal Diabetes Mellitus Managed with Continuous Subcutaneous Insulin Infusion (CSII) and Continuous Glucose Monitoring.
- Authors
Min Soo Kim; Sung Eun Kim; Na Yeong Lee; Seul Ki Kim; Shin Hee Kim; Won Kyoung Cho; Kyoung Soon Cho; Min Ho Jung; Byung-Kyu Suh; Moon Bae Ahn
- Abstract
Neonatal diabetes mellitus can be categorized as transient, permanent, or syndromic, and approximately half of the cases are transient. We present a case involving a term newborn who showed overt progression of transient neonatal diabetes mellitus, with complete remission within 6 months. On the second day of life, the patient presented with tachypnea, hyperglycemia, and decreased serum levels of C-peptide and insulin. Continuous subcutaneous infusion of insulin and continuous glucose monitoring were well tolerated. The patient showed a normal growth pattern, with no hyperglycemic or hypoglycemic episodes at 6 months of age. As it is rare and often asymptomatic, hyperglycemia may be attributed to various factors, including intrauterine environment, perinatal stress, and diverse genetic background. Therefore, consistent blood glucose monitoring and prompt early insulin therapy are crucial for any term newborns with persistent hyperglycemia, to prevent further diabetic complications. Moreover, continuous subcutaneous insulin infusion and the utilization of continuous glucose monitoring devices are the most effective and practical management strategies.
- Subjects
SUBCUTANEOUS infusions; HYPERGLYCEMIA; DIABETES; BLOOD sugar monitoring; GLUCOSE; BLOOD sugar monitors
- Publication
Neonatal Medicine, 2021, Vol 28, Issue 1, p41
- ISSN
2287-9412
- Publication type
Article
- DOI
10.5385/nm.2021.28.1.41