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- Title
Allergic broncho‐pulmonary aspergillosis: Old disease, new frontiers.
- Authors
Denton, Eve; Wark, Peter; Hew, Mark
- Abstract
Allergic bronchopulmonary aspergillosis (ABPA) is a disease of the airways caused by hypersensitivity to Aspergillus fumigatus or other Aspergillus spp. It occurs primarily in individuals with asthma or cystic fibrosis. The prevalence of ABPA varies by region, with the highest rates found in India. Diagnosis of ABPA is based on specific IgE levels and total IgE levels, as well as additional clinical and radiological features. Treatment involves reducing allergen exposure, using antifungal medications, and suppressing allergic inflammation. Monoclonal biologic therapies show promise as a potential treatment option.
- Subjects
PULMONARY aspergillosis; ASPERGILLOSIS; OBSTRUCTIVE lung diseases; IMMUNOGLOBULIN E; ASTHMATICS
- Publication
Respirology, 2024, Vol 29, Issue 8, p656
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/resp.14775