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Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.989169
By:
- Blokland, Kaj E. C.;
- Nizamoglu, Mehmet;
- Habibie, Habibie;
- Borghuis, Theo;
- Schuliga, Michael;
- Melgert, Barbro N.;
- Knight, Darryl A.;
- Brandsma, Corry-Anke;
- Pouwels, Simon D.;
- Burgess, Janette K.
Publication type:
Article
Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing.
Published in:
Pharmaceutics, 2020, v. 12, n. 4, p. 389, doi. 10.3390/pharmaceutics12040389
By:
- Blokland, Kaj E. C.;
- Waters, David W.;
- Schuliga, Michael;
- Read, Jane;
- Pouwels, Simon D.;
- Grainge, Christopher L.;
- Jaffar, Jade;
- Westall, Glen;
- Mutsaers, Steven E.;
- Prêle, Cecilia M.;
- Burgess, Janette K.;
- Knight, Darryl A.
Publication type:
Article
The Inflammatory Actions of Coagulant and Fibrinolytic Proteases in Disease.
Published in:
Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/437695
By:
- Schuliga, Michael
Publication type:
Article
The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.
Published in:
Scientific Reports, 2017, p. 41770, doi. 10.1038/srep41770
By:
- Schuliga, Michael;
- Jaffar, Jade;
- Harris, Trudi;
- Knight, Darryl A;
- Westall, Glen;
- Stewart, Alastair G
Publication type:
Article
NF-kappaB Signaling in Chronic Inflammatory Airway Disease.
Published in:
Biomolecules (2218-273X), 2015, v. 5, n. 3, p. 1266, doi. 10.3390/biom5031266
By:
- Schuliga, Michael
Publication type:
Article
ASK1ng to Delay the Progression of Pulmonary Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 5, p. 465, doi. 10.1165/rcmb.2022-0026ED
By:
- Schuliga, Michael;
- Madala, Satish K.
Publication type:
Article
The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 2, p. 200, doi. 10.1165/rcmb.2014-0419OC
By:
- Schuliga, Michael;
- Royce, Simon G.;
- Langenbach, Shenna;
- Berhan, Asres;
- Harris, Trudi;
- Keenan, Christine R.;
- Stewart, Alastair G.
Publication type:
Article
Plasminogen-Stimulated Inflammatory Cytokine Production by Airway Smooth Muscle Cells Is Regulated by Annexin A2.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 5, p. 751, doi. 10.1165/rcmb.2012-0404OC
By:
- Schuliga, Michael;
- Langenbach, Shenna;
- Xia, Yuxiu C.;
- Chengxue Qin;
- Mok, Josephine S. L.;
- Harris, Trudi;
- Mackay, Graham A.;
- Medcalf, Robert L.;
- Stewart, Alastair G.
Publication type:
Article
Transforming Growth Factor-β-Induced Differentiation of Airway Smooth Muscle Cells Is Inhibited by Fibroblast Growth Factor-2.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2013, v. 48, n. 3, p. 346, doi. 10.1165/rcmb.2012-0151OC
By:
- Schuliga, Michael;
- Javeed, Aqeel;
- Harris, Trudi;
- Yuxiu Xia;
- Chengxue Qin;
- Zhexing Wang;
- Xuehua Zhang;
- Lee, Peter V. S.;
- Camoretti-Mercado, Blanca;
- Stewart, Alastair G.
Publication type:
Article
Plasminogen Activation by Airway Smooth Muscle Is Regulated by Type I Collagen.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 6, p. 831, doi. 10.1165/rcmb.2009-0469OC
By:
- Schuliga, Michael;
- Harris, Trudi;
- Stewart, Alastair G.
Publication type:
Article
Functional Expression of IgG-Fc Receptors in Human Airway Smooth Muscle Cells.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 5, p. 665, doi. 10.1165/rcmb.2009-0371OC
By:
- Xia, YuXiu C.;
- Schuliga, Michael;
- Shepherd, Malcolm;
- Powell, Maree;
- Harris, Trudi;
- Langenbach, Shenna Y.;
- Tan, Peck Szee;
- Gerthoffer, William T.;
- Hogarth, P. Mark;
- Stewart, Alastair G.;
- Mackay, Graham A.
Publication type:
Article
Fibrillar Collagen Clamps Lung Mesenchymal Cells in a Nonproliferative and Noncontractile Phenotype.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2009, v. 41, n. 6, p. 731, doi. 10.1165/rcmb.2008-0361OC
By:
- Schuliga, Michael J.;
- See, Ian;
- Siau Chi Ong;
- Soon, Lilian;
- Camoretti-Mercado, Blanca;
- Harris, Trudi;
- Stewart, Alastair G.
Publication type:
Article
KCa3.1 Ca2+ -Activated K+ Channels Regulate Human Airway Smooth Muscle Proliferation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2007, v. 37, n. 5, p. 525, doi. 10.1165/rcmb.2006-0358OC
By:
- Shepherd, Malcolm C.;
- Duffy, S. Mark;
- Harris, Trudi;
- Cruse, Glenn;
- Schuliga, Michael;
- Brightling, Chris E.;
- Neylon, Craig B.;
- Bradding, Peter;
- Stewart, Alastair G.
Publication type:
Article
Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Published in:
Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 12, p. 5847, doi. 10.1111/jcmm.13855
By:
- Schuliga, Michael;
- Pechkovsky, Dmitri V;
- Read, Jane;
- Waters, David W;
- Blokland, Kaj E C;
- Reid, Andrew T;
- Hogaboam, Cory M;
- Khalil, Nasreen;
- Burgess, Janette K;
- Prêle, Cecilia M;
- Mutsaers, Steven E;
- Jaffar, Jade;
- Westall, Glen;
- Grainge, Christopher;
- Knight, Darryl A
Publication type:
Article
Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2.
Published in:
FASEB Journal, 2011, v. 25, n. 2, p. 483, doi. 10.1096/fj.09-154096
By:
- Khau, Thippadey;
- Langenbach, Shenna Y.;
- Schuliga, Michael;
- Harris, Trudi;
- Johnstone, Cameron N.;
- Anderson, Robin L.;
- Stewart, Alastair G.
Publication type:
Article
Upregulation of Glutathione-Related Genes and Enzyme Activities in Cultured Human Cells by Sublethal Concentrations of Inorganic Arsenic.
Published in:
Toxicological Sciences, 2002, v. 70, n. 2, p. 183, doi. 10.1093/toxsci/70.2.183
By:
- Schuliga, Michael;
- Chouchane, Salem;
- Snow, Elizabeth T.
Publication type:
Article
Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis.
Published in:
Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00738
By:
- Keenan, Christine R.;
- Langenbach, Shenna Y.;
- Jativa, Fernando;
- Harris, Trudi;
- Li, Meina;
- Chen, Qianyu;
- Xia, Yuxiu;
- Gao, Bryan;
- Schuliga, Michael J.;
- Jaffar, Jade;
- Prodanovic, Danica;
- Tu, Yan;
- Berhan, Asres;
- Lee, Peter V. S.;
- Westall, Glen P.;
- Stewart, Alastair G.
Publication type:
Article
Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells1.
Published in:
Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 3, p. 203, doi. 10.1139/cjpp-2014-0391
By:
- Keenan, Christine R.;
- Schuliga, Michael J.;
- Stewart, Alastair G.
Publication type:
Article
Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in mice.
Published in:
Canadian Journal of Physiology & Pharmacology, 2007, v. 85, n. 7, p. 727, doi. 10.1139/Y07-065
By:
- Langenbach, Shenna Y.;
- Wheaton, Ben J.;
- Fernandes, Darren J.;
- Jones, Catherine;
- Sutherland, Tara E.;
- Wraith, Bronwyn C.;
- Harris, Trudi;
- Schuliga, Michael J.;
- McLean, Catriona;
- Stewart, Alastair G.
Publication type:
Article
A Senescence Bystander Effect in Human Lung Fibroblasts.
Published in:
Biomedicines, 2021, v. 9, n. 9, p. 1162, doi. 10.3390/biomedicines9091162
By:
- Waters, David W.;
- Schuliga, Michael;
- Pathinayake, Prabuddha S.;
- Wei, Lan;
- Tan, Hui-Ying;
- Blokland, Kaj E. C.;
- Jaffar, Jade;
- Westall, Glen P.;
- Burgess, Janette K.;
- Prêle, Cecilia M.;
- Mutsaers, Steven E.;
- Grainge, Christopher L.;
- Knight, Darryl A.
Publication type:
Article
Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM.
Published in:
Cells (2073-4409), 2021, v. 10, n. 7, p. 1628, doi. 10.3390/cells10071628
By:
- Blokland, Kaj E. C.;
- Habibie, Habibie;
- Borghuis, Theo;
- Teitsma, Greta J.;
- Schuliga, Michael;
- Melgert, Barbro N.;
- Knight, Darryl A.;
- Brandsma, Corry-Anke;
- Pouwels, Simon D.;
- Burgess, Janette K.
Publication type:
Article
Stimulus-dependent glucocorticoid-resistance of GM-CSF production in human cultured airway smooth muscle.
Published in:
British Journal of Pharmacology, 2005, v. 145, n. 1, p. 123, doi. 10.1038/sj.bjp.0706174
By:
- Tran, Thai;
- Fernandes, Darren J;
- Schuliga, Michael;
- Harris, Trudi;
- Landells, Linda;
- Stewart, Alastair G
Publication type:
Article
The Role of Pathological Aging in Cardiac and Pulmonary Fibrosis.
Published in:
Aging & Disease, 2019, v. 10, n. 2, p. 419, doi. 10.14336/AD.2018.0601
By:
- Murtha, Lucy A.;
- Morten, Matthew;
- Schuliga, Michael J.;
- Mabotuwana, Nishani S.;
- Hardy, Sean A.;
- Waters, David W.;
- Burgess, Janette K.;
- Ngo, Doan T. M.;
- Sverdlov, Aaron L.;
- Knight, Darryl A.;
- Boyle, Andrew J.
Publication type:
Article
Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury.
Published in:
Clinical Science, 2024, v. 138, n. 8, p. 537, doi. 10.1042/CS20240220
By:
- Read, Jane;
- Reid, Andrew T.;
- Thomson, Claire;
- Plit, Marshall;
- Mejia, Ross;
- Knight, Darryl A.;
- Lize, Muriel;
- El Kasmi, Karim;
- Grainge, Christopher L.;
- Stahl, Heiko;
- Schuliga, Michael
Publication type:
Article
Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases.
Published in:
Clinical Science, 2020, v. 134, n. 20, p. 2681, doi. 10.1042/CS20190893
By:
- Blokland, Kaj E. C.;
- Pouwels, Simon D.;
- Schuliga, Michael;
- Knight, Darryl A.;
- Burgess, Janette K.
Publication type:
Article
Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner.
Published in:
Clinical Science, 2020, v. 134, n. 7, p. 889, doi. 10.1042/CS20191160
By:
- Schuliga, Michael;
- Read, Jane;
- Blokland, Kaj E. C.;
- Waters, David W.;
- Burgess, Janette;
- Prêle, Cecilia;
- Mutsaers, Steven E.;
- Jaffar, Jade;
- Westall, Glen;
- Reid, Andrew;
- James, Allen;
- Grainge, Christopher;
- Knight, Darryl A.
Publication type:
Article
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae.
Published in:
Science Translational Medicine, 2022, v. 14, n. 671, p. 1, doi. 10.1126/scitranslmed.abo5795
By:
- George, Peter M.;
- Reed, Anna;
- Desai, Sujal R.;
- Devaraj, Anand;
- Faiez, Tasnim Shahridan;
- Laverty, Sarah;
- Kanwal, Amama;
- Esneau, Camille;
- Liu, Michael K.C.;
- Kamal, Faisal;
- Man, William D.-C.;
- Kaul, Sundeep;
- Singh, Suveer;
- Lamb, Georgia;
- Faizi, Fatima K.;
- Schuliga, Michael;
- Read, Jane;
- Burgoyne, Thomas;
- Pinto, Andreia L.;
- Micallef, Jake
Publication type:
Article
The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis.
Published in:
Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00777
By:
- Murtha, Lucy A.;
- Schuliga, Michael J.;
- Mabotuwana, Nishani S.;
- Hardy, Sean A.;
- Waters, David W.;
- Burgess, Janette K.;
- Knight, Darryl A.;
- Boyle, Andrew J.
Publication type:
Article

Found: 28

Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts.

Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing.

The Inflammatory Actions of Coagulant and Fibrinolytic Proteases in Disease.

The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.

NF-kappaB Signaling in Chronic Inflammatory Airway Disease.

ASK1ng to Delay the Progression of Pulmonary Fibrosis.

The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.

Plasminogen-Stimulated Inflammatory Cytokine Production by Airway Smooth Muscle Cells Is Regulated by Annexin A2.

Transforming Growth Factor-β-Induced Differentiation of Airway Smooth Muscle Cells Is Inhibited by Fibroblast Growth Factor-2.

Plasminogen Activation by Airway Smooth Muscle Is Regulated by Type I Collagen.

Functional Expression of IgG-Fc Receptors in Human Airway Smooth Muscle Cells.

Fibrillar Collagen Clamps Lung Mesenchymal Cells in a Nonproliferative and Noncontractile Phenotype.

K<sub>Ca</sub>3.1 Ca<sup>2+</sup> -Activated K<sup>+</sup> Channels Regulate Human Airway Smooth Muscle Proliferation.

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.

Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2.

Upregulation of Glutathione-Related Genes and Enzyme Activities in Cultured Human Cells by Sublethal Concentrations of Inorganic Arsenic.

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis.

Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells<sup>1</sup>.

Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in mice.

A Senescence Bystander Effect in Human Lung Fibroblasts.

Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM.

Stimulus-dependent glucocorticoid-resistance of GM-CSF production in human cultured airway smooth muscle.

The Role of Pathological Aging in Cardiac and Pulmonary Fibrosis.

Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury.

Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases.

Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner.

A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae.

The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis.