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- Title
Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants in patients with hepatocellular carcinoma.
- Authors
Cicinnati, Vito R.; Zhang, Xia; Yu, Zhengya; Ferencik, Stanislav; Schmitz, Klaus J.; Dworacki, Grzegorz; Kaczmarek, Elzbieta; Oldhafer, Karl; Frilling, Andrea; Baba, Hideo A.; Schmid, Kurt W.; Grosse-Wilde, Hans; Broelsch, Christoph E.; DeLeo, Albert B.; Gerken, Guido; Beckebaum, Susanne
- Abstract
Wild-type (WT) sequence p53 peptides are attractive candidates for broadly applicable cancer vaccines. The aim of this study was to evaluate the potential of a WT p53-based immunotherapeutic approach for patients with hepatocellular carcinoma (HCC). Circulating CD8
- Publication
International Journal of Cancer, 2006, Vol 119, Issue 12, p2851
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.22251