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- Title
Endovascular management of HIV vasculopathy.
- Authors
Newcomer, Jack B.; Chishti, Emad A.; Raissi, Driss
- Abstract
HIV is a multisystem disease process that can affect the cardiovascular system resulting in vasculopathy. As highly active anti-retroviral therapy has allowed patients to live longer with the disease, vascular complications such as aneurysms, occlusive disease, spontaneous arteriovenous fistulae, and arterial dissections have been described. The pathogenesis of vascular-related complications in HIV is poorly understood but is thought to involve an interplay between viral-induced inflammation, vascular smooth muscle changes, endothelial alterations, and circulating blood factors. The most well-described management strategies for symptomatic aneurysm-related complications are surgical in nature, with mostly anecdotal reports of endovascular intervention. We present a case of a 24-year-old male who was found to have findings consistent with HIV vasculopathy on angiography after presenting with acute GI hemorrhage secondary to left gastric artery bleeding. Our patient was managed with endovascular embolization. Although studies have shown promise regarding the endovascular management of HIV-related aneurysmal complications in the short term, more research is needed to evaluate the long-term success of these interventions.
- Subjects
HIGHLY active antiretroviral therapy; ENDOVASCULAR surgery; VASCULAR diseases; VASCULAR smooth muscle; ARTERIAL dissections; HIV
- Publication
Journal of Clinical Imaging Science, 2022, Vol 12, p1
- ISSN
2156-7514
- Publication type
Article
- DOI
10.25259/JCIS_226_2021