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- Title
Treatment of refractory ulcerative necrobiosis lipoidica diabeticorum with oral thalidomide.
- Authors
Shah, Swapnil D.; Kale, Girish V.
- Abstract
Ulcerative necrobiosis lipoidica (NL) in diabetic patients is a rare, painful condition. It is a difficult-to-treat condition, impairing quality of life of patients. Although various drugs have been tried, none of them is consistently effective. Biologics in the form of TNF-alpha inhibitors show promising results in the treatment. But because of their high cost we chose thalidomide, which also has TNF-alpha inhibiting properties to successfully treat a long-standing case of ulcerative NL, which was refractory to various treatment modalities.
- Subjects
NECROBIOTIC disorders; DIABETES complications; THERAPEUTICS; THALIDOMIDE
- Publication
Indian Dermatology Online Journal, 2016, Vol 7, Issue 1, p43
- ISSN
2229-5178
- Publication type
Article
- DOI
10.4103/2229-5178.174328