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- Title
New Perspectives for Low Muscle Mass Quantity/Quality Assessment in Probable Sarcopenic Older Adults: An Exploratory Analysis Study.
- Authors
Besora-Moreno, Maria; Llauradó, Elisabet; Jiménez-ten Hoevel, Claudia; Sepúlveda, Cristina; Queral, Judit; Bernal, Glòria; Pérez-Merino, Laura; Martinez-Hervas, Sergio; Alabadi, Blanca; Ortega, Yolanda; Valls, Rosa Maria; Solà, Rosa; Pedret, Anna
- Abstract
Background: Low muscle mass quantity/quality is needed to confirm sarcopenia diagnosis; however, no validated cut-off points exist. This study aimed to determine the diagnostic accuracy of sarcopenia through muscle mass quantity/quality parameters, using the bioimpedance analysis (BIA), isokinetic, and ultrasound tools in probable sarcopenic community-dwelling older adults (≥60 years). Also, it aimed to suggest possible new cut-off points to confirm sarcopenia diagnosis. Methods: A cross-sectional exploratory analysis study was performed with probable sarcopenic and non-sarcopenic older adults. BIA, isokinetic, and ultrasound parameters were evaluated. The protocol was registered on ClinicalTrials.gov (NCT05485402). Results: A total of 50 individuals were included, 38 with probable sarcopenia (69.63 ± 4.14 years; 7 men and 31 women) and 12 non-sarcopenic (67.58 ± 4.54 years; 7 men and 5 women). The phase angle (cut-off: 5.10° men, p = 0.003; 4.95° women, p < 0.001), peak torque (cut-off: 66.75 Newtons-meters (N-m) men, p < 0.001; 48.35 N-m women, p < 0.001), total work (cut-off: 64.00 Joules (J) men, p = 0.007; 54.70 J women, p = 0.001), and mean power (cut-off: 87.8 Watts (W) men, p = 0.003; 48.95 W women, p = 0.008) in leg extension, as well as the the forearm muscle thickness (cut-off: 1.41 cm (cm) men, p = 0.017; 0.94 cm women, p = 0.041), had great diagnostic accuracy in both sexes. Conclusions: The phase angle, peak torque, total work, and mean power in leg extension, as well as forearm muscle thickness, had great diagnostic accuracy in regard to sarcopenia, and the suggested cut-off points could lead to the confirmation of sarcopenia diagnosis, but more studies are needed to confirm this.
- Subjects
CROSS-sectional method; EFFECT sizes (Statistics); SKELETAL muscle; INDEPENDENT living; BODY mass index; RECEIVER operating characteristic curves; T-test (Statistics); RESEARCH funding; BODY composition; SEX distribution; ULTRASONIC imaging; TORQUE; MANN Whitney U Test; DESCRIPTIVE statistics; RESEARCH; STATISTICS; QUALITY assurance; CONFIDENCE intervals; DATA analysis software; SARCOPENIA; OLD age
- Publication
Nutrients, 2024, Vol 16, Issue 10, p1496
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu16101496