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- Title
Acute Inositol-Stabilized Arginine Silicate Improves Cognitive Outcomes in Healthy Adults.
- Authors
Gills, Joshua L.; Campitelli, Anthony; Jones, Megan; Paulson, Sally; Myers, Jennifer Rae; Madero, Erica N.; Glenn, Jordan M.; Komorowski, James; Gray, Michelle
- Abstract
Inositol-stabilized arginine silicate (ASI) is an ergogenic aid that upregulates nitric oxide. Acute ASI supplementation improves working memory and processing speed in young adults but there is a lack of data examining other cognitive tasks. Therefore, the purpose of this study was to examine acute ASI effects on young healthy adults by assessing multiple cognitive domains. Nineteen young adults (20.9 ± 3.2 years) completed this randomized, double-blind, crossover study consuming ASI (1.5 g ASI + 12 g dextrose) and placebo (12 g dextrose). The participants completed the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and two digital cognitive assessments before consuming the supplement and then completed the same battery of tests 60 min post-supplementation. Repeated measures ANOVA demonstrated that ASI consumption significantly improved total RBANS and immediate memory scores compared to the placebo (p < 0.05). However, no significant differences were displayed between trials for other cognitive domains (p > 0.05). Acute ASI ingestion increased overall RBANS scores and immediate memory scores in young adults. More research is needed to examine the acute effects of ASI on other domains of cognition, in older populations, and its long-term effects on cognition.
- Subjects
SILICATES; MEMORY; ERGOGENIC aids; ANALYSIS of variance; ARGININE; COGNITION; DIETARY supplements; RANDOMIZED controlled trials; NEUROPSYCHOLOGICAL tests; PRE-tests &; post-tests; BLIND experiment; REPEATED measures design; DESCRIPTIVE statistics; STATISTICAL sampling; CROSSOVER trials; CONTROL groups; NITRIC oxide; INOSITOL; ADULTS
- Publication
Nutrients, 2021, Vol 13, Issue 12, p4272
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu13124272