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- Title
Rischio oncogeno nei lavoratori a turni: analisi della letteratura.
- Authors
Puligheddu, M.; Conti, S.; Campagna, M.; Meloni, M.; Pau, M.; Cocco, P.; Marrosu, F.
- Abstract
Introduction. According to IARC, shift work resulting in disruption of circadian rhythm is a probable human carcinogen (Group 2A). Methods. We examined the scientific literature on the carcinogenic risk among shift workers for risk assessment purposes. Results. Clock genes polymorphisms might contribute with suppression of melatonin synthesis, immuno-suppression from sleep deprivation, individual habits associated with shift work, and low vitamin D levels, in increasing risk of breast cancer, prostate cancer and lymphoma among shift workers. Conclusion. Although the epidemiological evidence seems scanty, the hypothesis that shift work-related sleep deprivation would contribute to increasing cancer risk seems based on solid ground.
- Publication
Giornale Italiano di Medicina del Lavoro ed Ergonomia, 2012, Vol 34, p624
- ISSN
1592-7830
- Publication type
Article