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- Title
Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden.
- Authors
Granerod, Julia; Huang, Yun; Davies, Nicholas W S; Sequeira, Patricia C; Mwapasa, Victor; Rupali, Priscilla; Michael, Benedict D; Solomon, Tom; Easton, Ava
- Abstract
Encephalitis affects people across the lifespan, has high rates of mortality and morbidity, and results in significant neurological sequelae with long-term consequences to quality of life and wider society. The true incidence is currently unknown due to inaccurate reporting systems. The disease burden of encephalitis is unequally distributed across the globe being highest in low- and middle-income countries where resources are limited. Here countries often lack diagnostic testing, with poor access to essential treatments and neurological services, and limited surveillance and vaccination programs. Many types of encephalitis are vaccine preventable, whereas others are treatable with early diagnosis and appropriate management. In this viewpoint, we provide a narrative review of key aspects of diagnosis, surveillance, treatment, and prevention of encephalitis and highlight priorities for public health, clinical management, and research, to reduce the disease burden.
- Subjects
PREVENTIVE medicine; MORTALITY prevention; TREATMENT of encephalitis; ENCEPHALITIS; IMMUNIZATION; GLOBAL burden of disease; PUBLIC health; MEDICAL research; EARLY diagnosis; EARLY medical intervention; HEALTH planning
- Publication
Clinical Infectious Diseases, 2023, Vol 77, Issue 11, p1552
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciad417