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- Title
Uncertainties in Screening and Prevention of Group B Streptococcus Disease.
- Authors
Doare, Kirsty Le; Heath, Paul T; Plumb, Jane; Owen, Natalie A; Brocklehurst, Peter; Chappell, Lucy C
- Abstract
In autumn 2016, the UK Department of Health (now Department of Health and Social Care) convened 2 meetings to discuss how to address research evidence gaps in order to minimize the impact of infant group B streptococcus (GBS) disease in the United Kingdom. At that meeting, a number of research priorities were highlighted, including improving the screening for GBS colonization in pregnant women, offering intrapartum antibiotic prophylaxis and point-of-care testing, and understanding the effect of widespread intrapartum antibiotic use on long-term infant health. Further discussions involved investigating the feasibility of a large prospective study of pregnant women and their infants in order to understand the role of antibodies in the protection against GBS disease in infancy following maternal exposure to GBS colonization. Here, we summarize the research uncertainties identified at that meeting.
- Subjects
UNITED Kingdom; THERAPEUTIC use of immunoglobulins; STREPTOCOCCAL disease diagnosis; STREPTOCOCCAL disease prevention; CHILD health services; HOST-bacteria relationships; IMMUNIZATION; MEDICAL screening; MEETINGS; MOTHER-infant relationship; PREGNANT women; PRIORITY (Philosophy); RESEARCH evaluation; STREPTOCOCCAL diseases; UNCERTAINTY; POINT-of-care testing; ANTIBIOTIC prophylaxis; MATERNAL exposure; INTRAPARTUM care; PREGNANCY
- Publication
Clinical Infectious Diseases, 2019, Vol 69, Issue 4, p720
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciy1069