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- Title
Kaposi's sarcoma and rheumatoid arthritis: a possible immunogenic and drug interaction.
- Authors
Satta, Rosanna; Cottoni, Francesca; Contu, Licinio; Mulargia, Marina; Montesu, M. Antonia
- Abstract
Background In the literature, Kaposi's sarcoma-rheumatoid arthritis association is reported and it has been suggested that genetic predisposition may play an important role. Numerous studies indicate that immunological deficiency may also have an important role in the pathogenesis of Kaposi's sarcoma, along with a series of others factors. Patients and methods We present two cases of Sardinian women with rheumathoid arthritis and Kaposi's sarcoma where the relationship between the drugs used for the treatment of the former (particularly gold salts) and Kaposi's sarcoma is highlighted, in addition, their genetic background is delineated. Conclusion. Our findings suggest that genetic background associated with drugs plays a role in the pathogenesis of Kaposi's sarcoma in rheumatoid arthritis patients.
- Subjects
KAPOSI'S sarcoma; RHEUMATOID arthritis; DRUG interactions; SALTS; CARCINOGENESIS; GENETICS; IMMUNODEFICIENCY
- Publication
Journal of the European Academy of Dermatology & Venereology, 1995, Vol 5, Issue 3, p269
- ISSN
0926-9959
- Publication type
Case Study
- DOI
10.1111/j.1468-3083.1995.tb00116.x