We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study.
- Authors
Pang, Philip Y. K.; Wee, Gillian H. L.; Hoo, Anne E. E.; Tahir Sheriff, Ismail Mohamed; See Lim Lim; Teing Ee Tan; Yee Jim Loh; Ka Lee Kerk; Yoong Kong Sin; Chong Hee Lim; Lim, See Lim; Tan, Teing Ee; Loh, Yee Jim; Kerk, Ka Lee; Sin, Yoong Kong; Lim, Chong Hee; Sheriff, Ismail Mohamed Tahir
- Abstract
Cardiac arrest with cerebral ischaemia frequently leads to severe neurological impairment. Extracorporeal life support (ECLS) has emerged as a valuable adjunct in resuscitation of cardiac arrest. Despite ECLS, the incidence of permanent neurological injury remains high. We hypothesize that patients receiving ECLS for cardiac arrest treated with therapeutic hypothermia at 34 °C have lower neurological complication rates compared to standard ECLS therapy at normothermia. Early results of this randomized study suggest that therapeutic hypothermia is safe in adult patients receiving ECLS, with similar complication rates as ECLS without hypothermia. Further studies are warranted to measure the efficacy of this therapy.
- Subjects
HYPOTHERMIA; LIFE support systems in critical care; CARDIAC arrest; NEUROLOGY; RANDOMIZED controlled trials; THERAPEUTICS; CENTRAL nervous system diseases; COMPARATIVE studies; CARDIOPULMONARY resuscitation; EXTRACORPOREAL membrane oxygenation; INDUCED hypothermia; RESEARCH methodology; MEDICAL cooperation; RESEARCH; EVALUATION research; DISEASE complications
- Publication
Journal of Cardiothoracic Surgery, 2016, Vol 11, p1
- ISSN
1749-8090
- Publication type
letter
- DOI
10.1186/s13019-016-0437-8