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- Title
Mitochondrial Monoamine Oxidase: Another Player in Pulmonary Hypertension?
- Authors
Sommer, Natascha; Schulz, Rainer
- Abstract
An editorial is presented on Pulmonary hypertension (PH) caused by pulmonary vascular remodeling leading to right heart hypertrophy and right heart failure. Topics include plethora of mechanisms leading to pulmonary vascular and right heart remodeling describing in animal models; and Reactive oxygen species (ROS) playing a key role in the activation of proliferative and antiapoptotic pathways underlying pulmonary vascular remodeling.
- Subjects
PULMONARY hypertension; VASCULAR remodeling; HYPERTROPHY; HEART failure; REACTIVE oxygen species
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2021, Vol 64, Issue 3, p277
- ISSN
1044-1549
- Publication type
Editorial
- DOI
10.1165/rcmb.2020-0523ED