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- Title
Preparation, characterization and antibacterial effects of eco-friendly gold nanorods.
- Authors
Awad, Manal A.; Hendi, Awatif A.; Virk, P.; Ortashi, Khalid M. O.; Elobeid, Mai A.; Merghani, Nada M.; Siddiqui, Muzzammil I.; Ibrahim, E. M.
- Abstract
Purpose: To synthesize and characterize eco-friendly gold nanorods (Au-NRs) and to assess their effects against two bacterial strains. Methods: Synthesis of eco-friendly gold nanorods was done from an aqueous solution of chloroauric acid and cetyltrimethylammonium bromide by mixing Olea europaea fruit and Acacia nilotica husk extracts with the latter as a reducing agent. The synthesis was monitored by ultraviolet-visible (UV) spectrophotmetry and a zetasizer, while the morphology of the resulting nanorods was assessed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM) coupled with an energy-dispersive spectrophotometer (EDS). The effect of the prepared eco-nanorods on growth of Escherichia coli and Staphylococcus aureus bacteria were investigated by agar diffusion method. Results: The synthesized Au-NRs were mostly rod-shaped, with mean size of 96 nm. They exhibited a potent antibacterial activity against Gram-positive and Gram-negative microorganisms (Escherichia coli and Staphylococcus aureus). Conclusion: The findings suggest that the nanoformulation of the biomaterial mix of Olea europaea fruit and Acacia nilotica husk extracts is a cost-effective, eco-friendly, and non-toxic synthesis of Au-NRs which has therpeautic potential.
- Subjects
ANTIBACTERIAL agents; GOLD nanoparticles; AQUEOUS solutions; CETYLTRIMETHYLAMMONIUM bromide; OLIVE; THERAPEUTICS
- Publication
Tropical Journal of Pharmaceutical Research, 2017, Vol 16, Issue 2, p313
- ISSN
1596-5996
- Publication type
Article
- DOI
10.4314/tjpr.v16i2.8