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- Title
Symptomatic treatment of brain metastases in renal cell carcinoma with sorafenib.
- Authors
Dongyan Hu; Yu Hu; Jisheng Li; Xiuwen Wang; Hu, Dongyan; Hu, Yu; Li, Jisheng; Wang, Xiuwen
- Abstract
Brain metastasis is synchronous to the diagnosis of renal cell carcinoma (RCC). The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months of 600 mg once daily sorafenib treatment who underwent right-sided nephrectomy. Further, withdrawal of sorafenib resulted in psychiatric changes along with increased metastasis lesions, which were recovered upon resuming the treatment, proposing that oral sorafenib can be used safely and efficiently for treatment of brain metastasis in advanced RCC.
- Subjects
RENAL cell carcinoma; BRAIN metastasis; NEPHRECTOMY; CANCER invasiveness; SORAFENIB
- Publication
Journal of Cancer Research & Therapeutics, 2018, Vol 14, pS1223
- ISSN
0973-1482
- Publication type
case study
- DOI
10.4103/0973-1482.189402