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- Title
Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer.
- Authors
Azami, Yusuke; Hayashi, Yuichiro; Nakamura, Tatsuya; Kimura, Kanako; Yamaguchi, Hisashi; Ono, Takashi; Takayama, Kanako; Hirose, Katsumi; Yabuuchi, Tomonori; Suzuki, Motohisa; Hatayama, Yoshiomi; Hareyama, Masato; Kikuchi, Yasuhiro; Fuwa, Nobukazu
- Abstract
The aim of this study was to evaluate the efficacy and safety of proton beam therapy for patients with locally recurrent parotid cancer. Between 2009 and 2012, ten patients with locally recurrent parotid gland cancer were treated with proton beam therapy (70.2 Gy equivalents in 32 fractions) with or without intra-arterial infusion chemotherapy of cisplatin (50 mg/body/week, for a total of 5–8 weeks). The median follow-up was 24 months (range 10–49 months). The 1-year overall survival and local control rates were 80 %, and the 3-year overall survival and local control rates were 60 %. None of the patients experienced grade 3–5 toxicities in the treatment or the follow-up periods. These findings suggest that proton beam therapy could be applied effectively and safely for patients with locally recurrent parotid gland cancer.
- Subjects
PROTON therapy; PAROTID glands; INTRA-arterial infusions; CANCER
- Publication
Indian Journal of Otolaryngology & Head & Neck Surgery, 2019, Vol 71, p49
- ISSN
2231-3796
- Publication type
Article
- DOI
10.1007/s12070-016-1008-y