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- Title
Perceived health modifies the effect of biomedical risk factors in the prediction of acute myocardial infarction. An incident case-control study from northern Sweden.
- Authors
Weinehall, L; Johnson, O; Jansson, J H; Boman, K; Huhtasaari, F; Hallmans, G; Dahlen, G H; Wall, S
- Abstract
<bold>Objectives: </bold>To assess the importance of biomedical risk factors, social factors and self-reported health in the prediction of the first event of acute myocardial infarction (AMI) in an apparently healthy middle-aged population.<bold>Design: </bold>An incident case-control study.<bold>Setting: </bold>The study was nested within the Västerbotten Intervention Program and the Northern Sweden MONICA cohorts.<bold>Subjects: </bold>The study consists of 78 AMI cases with two randomly selected controls per case from the same study cohorts.<bold>Results: </bold>Significant odds ratios were found for history of diabetes, daily smoking, cholesterol, body-mass index, hypertension, lower education and perceived ill health. In multivariate logistic regression smoking, hypertension and cholesterol of > or =7.8 mmol L(-1) remained significant. An interaction was observed between number of biomedical risk factors and perceived health.<bold>Conclusions: </bold>Smoking, hypertension and hypercholesterolaemia explain a major share of incident AMI events in a Swedish middle-aged population. The study further illustrates that perceived ill health negatively modifies the impact of these risk factors.
- Publication
Journal of Internal Medicine, 1998, Vol 243, Issue 2, p99
- ISSN
0954-6820
- Publication type
journal article
- DOI
10.1046/j.1365-2796.1998.00201.x