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- Title
Melanotic intracranial epidermoid: Case report and description of a new subtype.
- Authors
Sridhar, Krishnamurthy; Vij, Mukul
- Abstract
Intracranial epidermoids are generally seen as hypodense nonenhancing lesions on computed tomography scans; and, as T1 hypointense and T2 hyperintense lesions on magnetic resonance imaging (MRI). Unusual radiological findings have been reported earlier. The authors present the case of a 54-year old male patient who had prior intracranial surgery. On MRI, there was a thick peripheral mantle of diffusion restriction with a central core of brilliant T1 hyperintensity and very black T2 hypointensity. The peripheral mantle showing diffusion restriction was heterogeneously T1 hypointense and T2 hyperintense. At surgery, there was a typical pearly white epidermoid peripherally with a greenish-brown centre. Pathology showed abundant extracellular melanin which was also found in the basal layer. The authors present the first case of a melanin pigmented intracranial epidermoid in literature, describing a new histological subtype.
- Subjects
INTRACRANIAL tumors; COMPUTED tomography; MAGNETIC resonance imaging; DIFFUSION; PATHOLOGY; BRAIN diseases; MELANINS; EPIDERMAL cyst; INFRATENTORIAL brain tumors; DISEASE complications
- Publication
Neurology India, 2018, Vol 66, Issue 3, p763
- ISSN
0028-3886
- Publication type
case study
- DOI
10.4103/0028-3886.232336