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- Title
Arbovirus coinfection and co-transmission: A neglected public health concern?
- Authors
Vogels, Chantal B. F.; Rückert, Claudia; Cavany, Sean M.; Perkins, T. Alex; Ebel, Gregory D.; Grubaugh, Nathan D.
- Abstract
Epidemiological synergy between outbreaks of viruses transmitted by Aedes aegypti mosquitoes, such as chikungunya, dengue, and Zika viruses, has resulted in coinfection of humans with multiple viruses. Despite the potential impact on public health, we know only little about the occurrence and consequences of such coinfections. Here, we review the impact of coinfection on clinical disease in humans, discuss the possibility for co-transmission from mosquito to human, and describe a role for modeling transmission dynamics at various levels of co-transmission. Solving the mystery of virus coinfections will reveal whether they should be viewed as a serious concern for public health.
- Subjects
ARBOVIRUS diseases; EPIDEMIOLOGY; ZIKA virus; CHIKUNGUNYA; DENGUE
- Publication
PLoS Biology, 2019, Vol 17, Issue 1, p1
- ISSN
1544-9173
- Publication type
Article
- DOI
10.1371/journal.pbio.3000130