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- Title
New Dammarane-Type Saponins from Gynostemma pentaphyllum.
- Authors
Chen, Po-Yen; Chang, Chih-Chao; Huang, Hui-Chi; Zhang, Li-Jie; Liaw, Chia-Ching; Lin, Yu-Chi; Nguyen, Nham-Linh; Vo, Thanh-Hoa; Cheng, Yung-Yi; Morris-Natschke, Susan L.; Lee, Kuo-Hsiung; Kuo, Yao-Haur; Epifano, Francesco
- Abstract
Six new dammarane-type saponins, gypenosides CP1-6 (1–6), along with 19 known compounds 7–25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2).
- Subjects
APOPTOSIS; CANCER cells; CHEMICAL reactions; CELL lines; NANOPARTICLES
- Publication
Molecules, 2019, Vol 24, Issue 7, p1375
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules24071375