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- Title
First molecular characterization and phylogenetic analysis of the VP2 gene of feline panleukopenia virus in Bangladesh.
- Authors
Chowdhury, Q M Monzur Kader; Alam, Shahrul; Chowdhury, Md. Shahidur Rahman; Hasan, Mahmudul; Uddin, Md Bashir; Hossain, Md. Mukter; Islam, Md. Rafiqul; Rahman, Md. Masudur; Rahman, Md. Mahfujur
- Abstract
Feline panleukopenia virus (FPV) is a highly contagious infectious pathogen of cats globally. However, there is no information on the molecular identification and characterization of FPV in Bangladesh. Here, 8.16% (8/98) and 18.37% (18/98) of diarrheic cats tested positive for FPV by an immunochromatography (IC) test and PCR, respectively. The IC test showed 44.44% sensitivity and 100% specificity in comparison with PCR. Our newly sequenced Bangladeshi FPV strain (MN826076) showed the highest (99.71%) sequence identity to strains from the United Arab Emirates (UAE). Strain MN826076 contained two characteristic amino acid variations in VP2 identifying it as an FPV strain: valine at position 103 and aspartic acid at position 323. Phylogenetically, the VP2 of strain MN826076 was found to be closely related to 19 FPV strains, sharing the same clade.
- Subjects
BANGLADESH; UNITED Arab Emirates; ASPARTIC acid; SENSITIVITY &; specificity (Statistics); AMINO acids; VALINE; VIRUSES
- Publication
Archives of Virology, 2021, Vol 166, Issue 8, p2273
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-021-05113-y