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- Title
High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe.
- Authors
Istrate, Claudia; Sharma, Sumit; Nordgren, Johan; Videira e Castro, Sandra; Lopes, Ângela; Piedade, João; Zaky, Ahmed; Lima, António; Neves, Edgar; Veiga, José; Esteves, Aida
- Abstract
The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.
- Subjects
VIRAL diseases in children; ROTAVIRUS diseases; GASTROENTERITIS in children; LOW-income countries; VIRAL antigens; VIRUS phylogeny
- Publication
Archives of Virology, 2015, Vol 160, Issue 2, p423
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-014-2244-7