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- Title
Immunogenic Effects and Clinical Applications of Electroporation-Based Treatments.
- Authors
De Robertis, Mariangela; Signori, Emanuela
- Abstract
This document discusses the use of electroporation (EP) as a method for delivering drugs or genes to target cells in immunotherapy. EP has been shown to impact the immune system response by recruiting different types of immune cells and affecting both local and systemic immune reactions. The document highlights the various applications of EP in clinical and veterinary fields, including gene electrotransfer, electrochemotherapy, and irreversible electroporation. It also presents studies on optimizing EP protocols to minimize tissue damage and improve gene transfection efficiency or drug administration. The document concludes by summarizing the articles in a special issue that focus on the immunological outcomes and improvements of EP-based therapies in cancer treatment.
- Subjects
CLINICAL medicine; GENE transfection; THERAPEUTICS; TRANSMISSIBLE tumors; TREATMENT effectiveness
- Publication
Vaccines, 2024, Vol 12, Issue 1, p42
- ISSN
2076-393X
- Publication type
Article
- DOI
10.3390/vaccines12010042