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- Title
Use of the Endometriosis Fertility Index to Predict Natural Pregnancy after Endometriosis Surgery: A Single-Center Study.
- Authors
Kim, Jeong Sook; Lee, Chung Won; Yun, Jisun; Lee, Jae Hoon; Yun, Bo Hyun; Park, Joo Hyun; Seo, Seok Kyo; Cho, SiHyun; Choi, Young Sik; Lee, Byung Seok; Kim, Jeong Sook; Lee, Chung Won; Lee, Jae Hoon; Yun, Bo Hyun; Park, Joo Hyun; Seo, Seok Kyo; Choi, Young Sik; Lee, Byung Seok
- Abstract
<bold>Aims: </bold>Our objective was to predict natural pregnancy after endometriosis surgery using the endometriosis fertility index (EFI).<bold>Methods: </bold>A retrospective medical records review was conducted, examining patients surgically treated for endometriosis at a single center in Korea between January 2009 and February 2015. In total, 68 women attempting natural conception were analyzed by assessing age, preoperative serum CA-125, body mass index, revised American Fertility Society (rAFS) stage, EFI, and pregnancy outcome. Kaplan-Meier estimates and log-rank tests were used to generate cumulative natural pregnancy rate curves based on an EFI cut-point. A receiver-operating characteristic (ROC) curve was plotted for EFI.<bold>Results: </bold>Seventy-seven patients attempted conceptions, resulting in 33 natural and 9 assisted conceptions. Excluding assisted conceptions, the mean EFI scores of 68 women who were not pregnant and pregnant were 5.43 ± 0.36 and 6.88 ± 0.28 respectively. The relation between EFI and natural pregnancy was significant (cumulative overall pregnancy rate, p = 0.006), whereas rAFS stage was not (univariate logistics, p = 0.853). The cut-point for maximum natural pregnancy outcomes was 6 (area under ROC curve = 0.710, 95% CI 0.586-0.835).<bold>Conclusion: </bold>The EFI is a reliable staging system for predicting natural pregnancy after endometriosis surgery. EFI scores can be used to guide postoperative treatment of women with endometriosis.
- Subjects
SOUTH Korea; ENDOMETRIOSIS; FERTILITY; PREGNANCY; BODY mass index; HUMAN reproductive technology; BIRTH rate; INFERTILITY; EVALUATION of medical care; POSTOPERATIVE period; TUMOR antigens; RETROSPECTIVE studies; RECEIVER operating characteristic curves; KAPLAN-Meier estimator; DISEASE complications
- Publication
Gynecologic & Obstetric Investigation, 2019, Vol 84, Issue 1, p86
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000493264