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- Title
Neurofilament in CSF—A biomarker of disease activity and long-term prognosis in multiple sclerosis.
- Authors
Soelberg Sorensen, Per; Sellebjerg, Finn
- Abstract
The author suggest that serum studies of neurofilament concentrations maybe use as a surrogate outcome in future clinical trials, as routine biomarker of treatment response. He adds on neurofilament chains promising prognostic biomarkers but findings of the studies are small and needs evidence in larger trials or observational studies, he emphasizes the unsuitability of using daily clinical practice amidst acceptable repetation of lumbar punctures for cerebrospinal fluid analysis to patients.
- Subjects
CYTOPLASMIC filaments; CLINICAL trials; CEREBROSPINAL fluid; BIOMARKERS; SCIENTIFIC observation
- Publication
Multiple Sclerosis Journal, 2016, Vol 22, Issue 9, p1112
- ISSN
1352-4585
- Publication type
Editorial
- DOI
10.1177/1352458516658560