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- Title
Patient perspectives on physician conflict of interest in industry-sponsored clinical trials for multiple sclerosis therapeutics.
- Authors
Solomon, Andrew J.; Klein, Eran P.; Corboy, John R.; Bernat, James L.
- Abstract
Background: Pharmaceutical industry financial support of physicians, physician practices, and academic departments involved in multicenter industry-sponsored clinical trials of novel therapeutic agents is a relatively new and infrequently acknowledged source of potential physician conflict of interest. Detailed disclosure of these relationships to study participants is not uniformly a part of informed consent and documentation practices. Objective: To understand attitudes of patients with multiple sclerosis concerning disclosure of potential physician–industry conflicts of interest created by clinical trials and how such disclosures may influence study participation Methods: An anonymous online instrument was developed. Results: 597 people with multiple sclerosis participated in the study. The study found that detailed disclosure of conflicts of interest is important to potential participants in industry-sponsored clinical trials for multiple sclerosis therapies and that the presence of these conflicts of interest may influence patients’ decisions to participate in these studies. Conclusions: Findings from this study support a call for uniform guidelines regarding disclosure of physician–industry relationships to prospective research participants for industry-sponsored clinical trials.
- Subjects
CONFLICT of interests; COMMUNITY-based clinical trials; MULTIPLE sclerosis treatment; PHYSICIANS; PROFESSIONAL ethics; FINANCE
- Publication
Multiple Sclerosis Journal, 2015, Vol 21, Issue 12, p1593
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458515569101