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- Title
Commentary on ‘Disability outcome measures in multiple sclerosis clinical trials’.
- Authors
Noble, J Gareth; Osborne, Lisa A; Jones, Kerina H; Middleton, Rod M; Ford, David V
- Abstract
In order to fully understand and explore the effectiveness of any intervention for the management of multiple sclerosis (MS), it is important to have robust, valid, reliable, and universally applied measures. The recent article, ‘Disability outcome measures in multiple sclerosis clinical trials’ by Cohen, Reingold, Polman and Wolinsky (2012), explores this issue in regards to the effective measurement of MS-related disability, and the utilisation of patient-reported outcome measures, whilst highlighting the need for collaboration between the academic and clinical communities. Although it is important to examine disability measures, it is also equally important to recognise that physical function is only one aspect of a person’s experience; for example, quality of life and psychological well-being are also important aspects to assess. The application of e-health technologies and patient registers could be a useful method of gaining additional information, using patient-reported outcomes. This commentary explores these issues in relation to points raised by the Cohen et al. paper.
- Subjects
MULTIPLE sclerosis research; CLINICAL trials; DISABILITY identification; QUALITY of life; PSYCHOLOGICAL well-being; ELECTRONIC health records; MANAGEMENT; PHYSIOLOGY
- Publication
Multiple Sclerosis Journal, 2012, Vol 18, Issue 12, p1718
- ISSN
1352-4585
- Publication type
Opinion
- DOI
10.1177/1352458512457847