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- Title
PRELIMINARY STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF HEPTAMETHINE INDOCYANINE DYES FOR TUMOR-TARGETED IMAGING.
- Authors
GUO, QINYUAN; LUO, SHENGLIN; QI, QINGRONG; SHI, CHUNMENG
- Abstract
Our research has identified a couple of near-infrared (NIR) heptamethine indocyanine dyes exhibiting preferential tumor accumulation property for in vivo imaging. On the basis of our foregoing work, we describe here a preliminary structure-activity relationship (SAR) study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.
- Subjects
TUMOR diagnosis; NEAR infrared radiation; CYANINES; REACTIVE oxygen species; PHYSIOLOGICAL effects of chemicals
- Publication
Journal of Innovative Optical Health Sciences, 2013, Vol 6, Issue 1, p-1
- ISSN
1793-5458
- Publication type
Article
- DOI
10.1142/S179354581350003X