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- Title
Intestinal Permeability and Glucagon-like peptide-2 in Children with Autism: A Controlled Pilot Study.
- Authors
Robertson, Marli A.; Sigalet, David L.; Holst, Jens J.; Meddings, Jon B.; Wood, Julie; Sharkey, Keith A.
- Abstract
We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.
- Subjects
AUTISM in children; NUTRITION; INTESTINES; PEPTIDES; GASTROINTESTINAL diseases; CHILDREN with developmental disabilities; COMPARATIVE studies
- Publication
Journal of Autism & Developmental Disorders, 2008, Vol 38, Issue 6, p1066
- ISSN
0162-3257
- Publication type
Article
- DOI
10.1007/s10803-007-0482-1