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- Title
Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light.
- Authors
Pirchl, Michael; Kemmler, Georg; Humpel, Christian
- Abstract
Light intensity and wavelength strongly influence mood and cognition in humans and rodent animal models. The aim of the present study was to explore if dim white (7.6-17.7 lux) , blue (1.3-2.3 lux), and red light (0.8-1.4 lux) affect spatial memory of male and female Sprague Dawley rats in the 8-arm radial maze. Our data show that spatial memory significantly improved within 5 daily learning sessions (each 5 trials) under dim white light, which was not different between male and female rats. However, dim blue and red light significantly reduced spatial learning of female rats in the 8-arm radial maze in the last training session (session 5). In conclusion, we suggest that female Sprague Dawley rats show reduced learning under blue and red light.
- Subjects
BRIGHTNESS perception; HUMAN behavior; MEMORY disorders; EMOTIONS &; cognition; SPRAGUE Dawley rats; COGNITIVE structures; LABORATORY rats; PHOTOTHERAPY; PHOTORECEPTORS; ISOHORMONES
- Publication
International Journal of Zoology, 2010, p1
- ISSN
1687-8477
- Publication type
Article
- DOI
10.1155/2010/507524