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- Title
Neutropenia Accompanying Parvovirus B19 Infection after Gynecologic Surgery.
- Authors
Honda, Ken-ichi; Ishiko, Osamu; Tsujimura, Akemi; Hino, Masayuki; Hirai, Kouzo; Itoh, Fumihiro; Tanaka, Tetsuji; Ogita, Sachio
- Abstract
The hematologic data and symptoms of 7 patients seropositive for parvovirus B19 IgM antibody after gynecologic surgery were analysed. Parvovirus may have been transmitted by fibrin glue prepared from heat-treated human plasma and used for hemostasis during surgery. The peripheral blood neutrophil count decreased to below 1 × 10[sup 9] /l between postoperative day (POD) 10 and 18, but recovered spontaneously to within the normal range. G-CSF injection was effective in preventing neutropenia or obtaining a prompt recovery. The reticulocyte count fell below 10 × 10[sup 9] /l between POD 13 and 19, and also recovered spontaneously. A slapped-cheek rash was not observed in any of the 7 patients.Copyright © 2000 S. Karger AG, Basel
- Subjects
PARVOVIRUSES; PARVOVIRUS diseases; NEUTROPENIA; RETICULOCYTES; FIBRIN tissue adhesive; BLOOD plasma substitutes; BLOOD cell count; GYNECOLOGIC surgery; GRANULOCYTE-colony stimulating factor; SERUM; SURGICAL hemostasis; NEUTROPHILS
- Publication
Acta Haematologica, 2000, Vol 103, Issue 4, p186
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000041047