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- Title
Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.
- Authors
Herrero-Martin, David; Fourtouna, Argyro; Niedan, Stephan; Riedmann, Lucia T.; Schwentner, Raphaela; Aryee, Dave N. T.
- Abstract
Ewing's sarcoma family tumors (ESFT) are characterized by specific chromosomal translocations, which give rise to EWS-ETS chimeric proteins. These aberrant transcription factors are the main pathogenic drivers of ESFT. Elucidation of the factors influencing EWS-ETS expression and or activity will guide the development of novel therapeutic agents against this fatal disease.
- Publication
Sarcoma, 2011, p1
- ISSN
1357-714X
- Publication type
Journal Article
- DOI
2011/352580