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- Title
Deposit Effects on Plate-haptic Rotationally Asymmetric Refractive Multifocal Intraocular Lens with +1.5D Addition Power.
- Authors
Takashi MATSUSHIMA; Kenji KAWAI
- Abstract
Objective: To evaluate the optical performance of plate-haptic rotationally asymmetric refractive multifocal intraocular lenses (IOLs) with + 1.5 D addition power by reproducing calcium deposition using rabbit eyes. Methods: Five IOLs (LS-313 MF15 [Santen/Teleon], W-60R [Santen], NS1 [KOWA], SY60WF [Alcon], and NS-60YS [NIDEK]) with varying water content were randomly implanted in rabbit eyes. Cell proliferation in the lens capsule and deposits on the IOL surface were confirmed with a slit lamp. The surface deposits were stained with alizarin red, and IOL transmittance was measured with a spectrophotometer. IOL storage solutions were analyzed using inductively coupled plasma mass spectrometry to confirm the presence of calcium. Results: Slit-lamp observations revealed abundant cellular proliferation on all IOLs. Granular deposits, unlike proliferating cells, were observed on LS-313 MF15 lenses two months after surgery, increasing over time, and stained red. The transmittance of LS-313 MF15 decreased in correlation with the stained area. Calcium was detected in all IOL storage solutions; however, deposits were confirmed only on the LS-313 MF15 surface, indicating decreased transmittance. Conclusion: These findings can facilitate predicting deposition on IOLs in clinical settings and selecting IOL materials for long-term stability. The long-term use of LS-313 MF15 IOLs requires further verification to avoid post-surgical extraction.
- Subjects
INTRAOCULAR lenses; CALCIFICATION; CELL proliferation; SPECTROPHOTOMETERS; SURGERY
- Publication
Tokai Journal of Experimental & Clinical Medicine, 2023, Vol 48, Issue 4, p105
- ISSN
0385-0005
- Publication type
Article