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- Title
Propafenone-Induced Torsade de Pointes: Cross-Reactivity with Quinidine.
- Authors
Hii, Johy T. Y.; Wyse, D. George; Gillis, Anne M.; Cohen, James M.; Mitchell, L. Brent
- Abstract
A 77-year-old female with new onset atrial fibrillation occurring in the absence of structural heart disease developed torsade de pointes during therapy with quinidine bisulfate 500 mg orally every 8 hours. Ten days after quinidine therapy had been discontinued she developed torsade de pointes whiJe receiving propafenone 300 mg orally every 8 hours. This case demonstrates that propafenone may be associated with torsade de pointes and suggests a cross-reactivity between this effect and prior occurrence of torsade de pointes on Class IA antiarrhythmic drug therapy.
- Subjects
PROPAFENONE; MYOCARDIAL depressants; QUINIDINE; VENTRICULAR tachycardia; CARDIOLOGY
- Publication
Pacing & Clinical Electrophysiology, 1991, Vol 14, Issue 11, p1568
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.1991.tb02729.x