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- Title
Genotyping of hepatitis C virus isolates from Basque Country, Spain.
- Authors
Cilla, G.; García-Bengoechea, M.; Trallero, E. Perez; Montalvo, I.; Vicente, D.; Arenas, J. I.
- Abstract
The genotype of HCV was determined in 161 chronic HCV-infected patients. The patients were classified into three groups on the basis of the origin of the HCV infection: 50 patients had a history of intravenous drug use (IVDU) but no HIV infection; 41 patients had received blood transfusions, and 70 patients had no known exposure. The distribution of HCV genotypes was associated with the origin of infection and age of patients: genotype 1b was predominant among patients who had received blood transfusions and those without evidence of parenteral exposure (84·6% and 67·7%, respectively), whereas genotype 3a was present in 65·3% of IVDUs. Patients with genotype 1b were older than those with genotypes la or 3a: 50·3 ± 12 vs. 34·1±9·9 and 31 ± 5.4 years, respectively. These findings suggest that the pattern of HCV genotypes in our region is changing and that genotype 1b may be substituted by 3a as the dominant genotype in the future.
- Publication
Epidemiology & Infection, 1996, Vol 117, Issue 3, p533
- ISSN
0950-2688
- Publication type
Article
- DOI
10.1017/S0950268800059227