We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Salivary Extracellular Vesicles: Biomarkers and Beyond in Human Diseases.
- Authors
Wu, Jialing; Liu, Gege; Jia, Rong; Guo, Jihua
- Abstract
Extracellular vesicles, as bioactive molecules, have been extensively studied. There are abundant studies in the literature on their biogenesis, secretion, structure, and content, and their roles in pathophysiological processes. Extracellular vesicles have been reviewed as biomarkers for use in diagnostic tools. Saliva contains many extracellular vesicles, and compared with other body fluids, it is easier to obtain in a non-invasive way, making its acquisition more easily accepted by patients. In recent years, there have been numerous new studies investigating the role of salivary extracellular vesicles as biomarkers. These studies have significant implications for future clinical diagnosis. Therefore, in this paper, we summarize and review the potential applications of salivary extracellular vesicles as biomarkers, and we also describe their other functions (e.g., hemostasis, innate immune defense) in both oral and non-oral diseases.
- Subjects
EXTRACELLULAR vesicles; POLYMERSOMES; BIOMARKERS; BODY fluids; SALIVA; ORAL diseases; VESICLES (Cytology)
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 24, p17328
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms242417328