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- Title
Prevalence and epidemiological and histopathological features of canine cutaneous mast cell tumours in Uberlândia, Brazil.
- Authors
Costa, Marcelo Carrijo; Aprígio Silva, Ana Letícia Daher; Moreira, Thais Almeida; Gundim, Lígia Fernandes; Medeiros-Ronchi, Alessandra Aparecida
- Abstract
This study aimed to perform a retrospective survey of canine cutaneous mast cell tumours at the Veterinary Hospital of the Federal University of Uberlândia, as well as to gather epidemiological data, such as breed, age, sex, and location. We also sought to histopathologically classify and characterize the mast cell tumours. Mast cell tumour was the most common neoplasm, accounting for 16.78% of skin neoplasms. In terms of the epidemiological data, the mast cell tumours did not show sexual predilection. Animals aged 9 to 12 years were the most affected (44.14%). The genitalia were the most frequent location (28.15%), and mongrel dogs showed the highest prevalence (30.43%), followed by boxers (22.61%). A total of 92 slides were classified; grade II was most frequently seen (61.96%). Statistically, injuries such as necrosis, oedema, and haemorrhage were not related with histological classification (P > 0.05). Finally, the mitotic index was related to tumour grade (P < 0.05), and can act as an instrument for histological classification of these tumours. Mast cell tumour is the most common neoplasm in dogs, with no sex predilection. Contrary to what was expected, oedema, necrosis and haemorrhage do not increase according to graduation and can be seen in all classifications. Mitotic index is the best indicator to classify these neoplasms.
- Subjects
CONNECTIVE tissue cells; BASOPHILS; MAST cell tumors; SKIN cancer; GENITALIA
- Publication
Acta Veterinaria Brno, 2017, Vol 86, Issue 2, p189
- ISSN
0001-7213
- Publication type
Article
- DOI
10.2754/avb201786020189