We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genetic history of an archaic hominin group from Denisova Cave in Siberia.
- Authors
Reich, David; Green, Richard E.; Kircher, Martin; Krause, Johannes; Patterson, Nick; Durand56, Eric Y.; Viola, Bence; Briggs, Adrian W.; Stenzel, Udo; Johnson, Philip L. F.; Maricic, Tomislav; Good, Jeffrey M.; Marques-Bonet, Tomas; Alkan, Can; Qiaomei Fu; Mallick, Swapan; Heng Li; Meyer, Matthias; Eichler, Evan E.; Stoneking, Mark
- Abstract
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4-6% of its genetic material to the genomes of present-day Melanesians. We designate this hominin population 'Denisovans' and suggest that it may have been widespread in Asia during the Late Pleistocene epoch. A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone. This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
- Subjects
SIBERIA (Russia); RUSSIA; DEOXYRIBOSE; GENOMES; GENE expression; DENISOVA Cave (Russia)
- Publication
Nature, 2010, Vol 468, Issue 7327, p1053
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/nature09710