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- Title
Antimicrobial Activity and Chemical Composition Analysis of Jasminum sambac L. and Plumeria alba L. Flower Extracts.
- Authors
Rakhmawati, Anna
- Abstract
Jasminum sambac L. and Plumeria alba L. are known to have antimicrobial properties. This research was conducted to determine the antimicrobial activity and chemical composition of crude ethanol extracts from J. sambac and P. alba flowers. J. sambac and P. alba flowers were obtained, air-dried, and extracted with ethanol. The final J. sambac and P. alba flower ethanol extracts were prepared in ratios of 1:1, 1:2, and 2:1, with concentrations of 25 and 50 mg/mL, respectively. Antimicrobial activity was tested against Staphylococcus aureus, Escherichia coli and Candida albicans. Qualitative phytochemical and Gas Chromatography-Mass Spectrometry (GC-MS) analyses were conducted to determine the phytoconstituents of the flower extracts. The maximum inhibition zone of J. sambac and P. alba (1:2) ratio against S. aureus (8.68±0.15 mm) and E. coli (8.59±0.09 mm) was obtained at 50 and 25 mg/mL for 6 h, respectively. Furthermore, the highest C. albicans inhibition zone of 7.54±0.27 mm was achieved after 24 h using a 25 mg/mL J. sambac: P. alba (2:1) ratio. The phytochemical analysis showed that both flower extracts contained tannin, flavonoid, saponin, and phenol. After that, GC-MS analysis of J. sambac revealed 24 compounds, the majority of which were made up of 9,12,15-octadecatrienal, octadecanoic acid, and 9,12-octadecadienoic acid. There were 44 compounds with a higher percentage of cyclohexanol, octadecanoic acid, and squalene in the Plumeria alba GC-MS analysis. The findings of this study suggest that ethanol extracts of J. sambac and P. alba flowers could be employed as antibacterial agents.
- Subjects
ANTI-infective agents; ETHANOL; PHYTOCHEMICALS; STEARIC acid; SQUALENE
- Publication
Tropical Journal of Natural Product Research, 2022, Vol 6, Issue 3, p330
- ISSN
2616-0684
- Publication type
Article
- DOI
10.26538/tjnpr/v6i3.6