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- Title
胃肠道肿瘤患者术中联合腹腔热灌注化学治疗对术后胃肠功能恢复的影响因素分析
- Authors
杨华; 陈青; 邓力; 曹烨; 李文翔; 徐静; 王炯元; 童汉兴; 周宇红; 张勇; 陆维祺
- Abstract
Objective · To investigate the effect of hyperthermic intraperitoneal chemotherapy on postoperative gastrointestinal function recovery in patients with gastrointestinal cancer. Methods · Sixty-two cases of gastrointestinal cancer patients were enrolled who accepted cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in Department of General Surgery, Shanghai Public Health Clinical Center, Fudan University, from July 2014 to June 2017. The gastrointestinal function of patients were evaluated according to the I-FEED scoring system. The patients were divided into normal recovery group (I-FEED score<6, n=38) and delayed recovery group (I-FEED score ≥ 6, n=24) . Univariate and multivariate Logistic analyses were performed on characteristic factors that may affect the recovery of postoperative gastrointestinal function including gender, age, presence of diabetes, preoperative albumin, and so on. Results · There were significantly differences in the preoperative serum albumin level (P=0.040) , intraoperative bleeding (P=0.044) ,the time of extraction of the peritoneal cavity drainage tube (P=0.026) , the time of urethral tube extraction (P=0.021) and the time of hospitalization (P=0.017) in the two groups of patients with normal or delayed gastrointestinal function recovery. Multivariate Logistic regression results suggested that preoperative serum albumin level may be beneficial for the recovery of postoperative gastrointestinal function (OR=0.84, 95% CI 0.17-4.27, P=0.041) .Conclusion · The preoperative serum albumin level can be used as an independent predictor of postoperative gastrointestinal functional recovery in patients with gastrointestinal cancer after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy.
- Publication
Journal of Shanghai Jiaotong University (Medical Science), 2019, Vol 39, Issue 4, p407
- ISSN
1674-8115
- Publication type
Article
- DOI
10.3969/j.issn.1674-8115.2019.04.014