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- Title
Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections.
- Authors
Lodise, Thomas P; Scheetz, Marc; Carreno, Joseph J; Chambers, Henry; Fowler, Vance; Holland, Thomas L
- Abstract
Among patients with methicillin-resistant Staphylococcus aureus bacteremia, vancomycin-associated acute kidney injury increased as a function of the day 2 area under the curve (AUC), even for daily AUCs within the recommended therapeutic range (400–600). Further data are needed to determine if daily AUCs <400 can be maintained without compromising efficacy.
- Subjects
STAPHYLOCOCCUS aureus infections; METHICILLIN-resistant staphylococcus aureus; ACUTE kidney failure; VANCOMYCIN; BACTEREMIA
- Publication
Open Forum Infectious Diseases, 2022, Vol 9, Issue 2, p1
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofab651