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Differential disposition of intra-renal generated and preformed glucuronides: studies with 4-methylumbelliferone and 4-methylumbelliferyl glucuronide in the filtering and nonfiltering isolated perfused rat kidney.
- Published in:
- Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 4, p. 507, doi. 10.1111/j.2042-7158.2010.01244.x
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- Publication type:
- Article
Pharmacogenomics of CYP2C9: Functional and Clinical Considerations.
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- Journal of Personalized Medicine, 2018, v. 8, n. 1, p. 1, doi. 10.3390/jpm8010001
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- Publication type:
- Article
Polymorphisms in UDP Glucuronosyltransferase Genes: Functional Consequences and Clinical Relevance.
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- Clinical Chemistry & Laboratory Medicine, 2000, v. 38, n. 9, p. 889
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- Publication type:
- Article
Evolution of drug metabolism: Hitchhiking the technology bandwagon.
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- Clinical & Experimental Pharmacology & Physiology, 2002, v. 29, n. 11, p. 1040, doi. 10.1046/j.1440-1681.2002.03768.x
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- Publication type:
- Article
Application of Model Informed Precision Dosing to Address the Impact of Pregnancy Stage and CYP2D6 Phenotype on Foetal Morphine Exposure.
- Published in:
- AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00541-1
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- Publication type:
- Article
Dispositional factors do not contribute to the enantiospecificity of the cardiovascular effects of phenylpropanolamine.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 55, n. 1, p. 35, doi. 10.1038/clpt.1994.7
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- Publication type:
- Article
Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers.
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- Clinical Pharmacology & Therapeutics, 1990, v. 47, n. 3, p. 403, doi. 10.1038/clpt.1990.46
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- Publication type:
- Article
Response to <italic>in vitro</italic> and physiologically‐based pharmacokinetic assessment of the drug–drug interaction potential of canagliflozin.
- Published in:
- 2018
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- Publication type:
- Letter to the Editor
Scaling factors for the in vitro- in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 81, n. 6, p. 1153, doi. 10.1111/bcp.12889
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- Publication type:
- Article
Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 ( CYP) and UDP-glucuronosyltransferase ( UGT).
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- British Journal of Clinical Pharmacology, 2013, v. 76, p. 587, doi. 10.1111/bcp.12086
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- Publication type:
- Article
Renal drug metabolism in humans: the potential for drug–endobiotic interactions involving cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT).
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- British Journal of Clinical Pharmacology, 2013, v. 76, n. 4, p. 587, doi. 10.1111/bcp.12086
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- Publication type:
- Article
Perpetrators of pharmacokinetic drug-drug interactions arising from altered cytochrome P450 activity: a criteria-based assessment.
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- British Journal of Clinical Pharmacology, 2011, v. 71, n. 5, p. 727, doi. 10.1111/j.1365-2125.2011.03903.x
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- Publication type:
- Article
What's in a name?
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 5, p. 785, doi. 10.1111/j.1365-2125.2010.03817.x
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- Publication type:
- Article
Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: Inhibition by NSAIDs.
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- British Journal of Clinical Pharmacology, 2009, v. 68, n. 3, p. 402, doi. 10.1111/j.1365-2125.2009.03469.x
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- Publication type:
- Article
Macrolide–theophylline interactions: no role for the inhibition of cytochrome P4501A2.
- Published in:
- 2008
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- Publication type:
- Letter
Time-dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants.
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- British Journal of Clinical Pharmacology, 2008, v. 65, n. 1, p. 87, doi. 10.1111/j.1365-2125.2007.02964.x
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- Publication type:
- Article
Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.
- Published in:
- European Journal of Clinical Pharmacology, 2019, v. 75, n. 9, p. 1211, doi. 10.1007/s00228-019-02682-5
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- Publication type:
- Article
Assessment of inter-individual variability in predicted phenytoin clearance.
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- European Journal of Clinical Pharmacology, 2009, v. 65, n. 12, p. 1203, doi. 10.1007/s00228-009-0703-y
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- Publication type:
- Article
Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate.
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- European Journal of Clinical Pharmacology, 2006, v. 62, n. 3, p. 203, doi. 10.1007/s00228-005-0091-x
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- Publication type:
- Article
Relationship between vemurafenib plasma concentrations and survival outcomes in patients with advanced melanoma.
- Published in:
- 2020
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- Publication type:
- journal article
Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination.
- Published in:
- British Journal of Clinical Pharmacology, 2007, v. 64, n. 4, p. 450, doi. 10.1111/j.1365-2125.2007.02943.x
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- Publication type:
- Article
Quality of requests for serum digoxin concentrations: experience from an Australian Regional Health Service.
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- British Journal of Clinical Pharmacology, 2007, v. 63, n. 5, p. 623, doi. 10.1111/j.1365-2125.2006.02802.x
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- Publication type:
- Article
Authors' reply: Nonselective nonsteroidal anti-inflammatory drugs and increased cardiovascular events: emotional stress could be the explanation.
- Published in:
- 2007
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- Publication type:
- Letter
Relationships between the adverse effects of drugs and genetic polymorphism in genes encoding drug metabolizing enzymes.
- Published in:
- 2007
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- Publication type:
- Letter
Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation.
- Published in:
- British Journal of Clinical Pharmacology, 2006, v. 61, n. 4, p. 427, doi. 10.1111/j.1365-2125.2006.02588.x
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- Publication type:
- Article
Non-selective nonsteroidal anti-inflammatory drugs and cardiovascular events: is aldosterone the silent partner in crime?
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- British Journal of Clinical Pharmacology, 2006, v. 61, n. 6, p. 738, doi. 10.1111/j.1365-2125.2006.02678.x
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- Publication type:
- Article
An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.
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- British Journal of Clinical Pharmacology, 2006, v. 61, n. 5, p. 570, doi. 10.1111/j.1365-2125.2006.02627.x
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- Publication type:
- Article
S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.
- Published in:
- British Journal of Clinical Pharmacology, 2005, v. 60, n. 4, p. 423, doi. 10.1111/j.1365-2125.2005.02446.x
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- Publication type:
- Article
In vitro–in vivo correlations for drugs eliminated by glucuronidation: Investigations with the model substrate zidovudine.
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- British Journal of Clinical Pharmacology, 2002, v. 54, n. 5, p. 493, doi. 10.1046/j.1365-2125.2002.01669.x
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- Publication type:
- Article
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes.
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- British Journal of Clinical Pharmacology, 2001, v. 52, n. 5, p. 605, doi. 10.1046/j.0306-5251.2001.01487.x
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- Publication type:
- Article
The xenobiotic inhibitor profile of cytochrome P4502C8.
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- British Journal of Clinical Pharmacology, 2000, v. 50, n. 6, p. 573, doi. 10.1046/j.1365-2125.2000.00316.x
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- Publication type:
- Article
Nonspecific binding of drugs to human liver microsomes.
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- British Journal of Clinical Pharmacology, 2000, v. 49, n. 5, p. 453, doi. 10.1046/j.1365-2125.2000.00193.x
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- Publication type:
- Article
Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism.
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- British Journal of Clinical Pharmacology, 1999, v. 47, n. 3, doi. 10.1046/j.1365-2125.1999.00890.x
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- Publication type:
- Article
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism.
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- British Journal of Clinical Pharmacology, 1998, v. 45, n. 6, p. 525, doi. 10.1046/j.1365-2125.1998.00721.x
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- Publication type:
- Article
Limited value of the urinary phenytoin metabolic ratio for the assessment of cytochrome P4502C9 activity in vivo.
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- British Journal of Clinical Pharmacology, 1996, v. 42, n. 6, p. 774, doi. 10.1046/j.1365-2125.1996.00496.x
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- Publication type:
- Article
Characterisation of the Binding of Cationic Amphiphilic Drugs to Phospholipid Bilayers Using Surface Plasmon Resonance.
- Published in:
- ChemMedChem, 2007, v. 2, n. 3, p. 366, doi. 10.1002/cmdc.200600252
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- Publication type:
- Article
Assessment of caffeine exposure: Caffeine content of beverages, caffeine intake, and plasma concentrations of methylxanthines.
- Published in:
- Clinical Pharmacology & Therapeutics, 1986, v. 39, n. 1, p. 54, doi. 10.1038/clpt.1986.10
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- Publication type:
- Article
Determinants of acetaminophen metabolism: Effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways.
- Published in:
- Clinical Pharmacology & Therapeutics, 1984, v. 35, n. 4, p. 480, doi. 10.1038/clpt.1984.64
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- Publication type:
- Article